A 19-Year-Old Man with a History of Recreational Inhalation of Nitrous Oxide with Severe Peripheral Neuropathy and Central Pulmonary Embolism

11 August 2021: Articles

Unusual clinical course, Challenging differential diagnosis

Oliver Buchhave Pedersen ^C , Anne-Mette Hvas ^C , Erik Lerkevang Grove ^A*

DOI: 10.12659/AJCR.931936

Am J Case Rep 2021; 22:e931936

Table 1. Laboratory values at admission, during hospitalization, and at 6-month clinical follow-up.

Laboratory values	Admission	Hospitalization	6-Month follow-up	Reference ranges

Potassium, mmol/L	3.5	3.8		3.5–4.6
Sodium, mmol/L	140	139		137–145
Calcium, mmol/L	2.20	2.52		2.20–2.55
Albumin, g/L	36	36		36–48
CRP, mg/L	6.9	5.8
Leucocytes, ×10/L	6.2	9.1		3.50–10.0
Creatinine, µmol/L	61	62		60–105

Hemoglobin, mmol/L	9.3	8.7	10.5	8.3–10.5
Erythrocytes MCV, fl	101	99	93	82–102
Erythrocytes MCHC, mmol/L	22.1	21.5	21.1	19.7–22.2
Platelets, ×10/L	384	346	342	145–350
Iron, µmol/L	26			9–34
Vitamin B, pmol/L	234	352		200–600
Methylmalonic acid, µmol/L	>10			0.08–0.28
Folate, µmol/L	21			>9
Homocysteine, µmol/L	92		9.5

INR	1.2	1.2	1.1
APTT	23		26	20–29
Fibrin D-dimer, mg/L		3.0	0.25
Cardiac troponin I, ng/L
Cardiolipinantibodies, IgG, ×10 IU/L			16
Cardiolipinantibodies, IgM, ×10 IU/L
Lupus anticoagulant			1.2
Coagulation factor VIII, ×10 IU/L			1.34	0.66–1.55
Antithrombin, ×10 IU/L			0.84	0.80–1.20
Protein-C, ×10 IU/L			0.93	0.74–1.50
Protein-S, ×10 IU/L			0.70	0.69–1.37
DNA-F2-gene			Normal
DNA-F5-gene			Normal
Anti-beta-2-glycoprotein 1 antibodies, IgG, ×10 IU/L
Anti-beta-2-glycoprotein 1 antibodies, IgM, ×10 IU/L

Leucocytes, ×10/L		0
Mononuclear leucocytes, ×10/L		0
Polynuclear leucocytes, ×10/L		0
Glucose, mmol/L		3.6		2.5–4.5
Protein, g/L		0.26		0.15–0.50
Erythrocytes, ×10/L		0		0
CRP – C-reactive protein; MCV – mean cell volume; MCHC – mean cell hemoglobin concentration; INR – international normalized ratio; APTT – activated partial thromboplastin time; IU – international units.