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03 July 2021: Articles

Thrombocytopenia Induced by Polysulfone Dialysis Membranes

Unusual or unexpected effect of treatment

Ivan Claudio-Gonzalez B , Deepak Ravindranathan B , Christine L. Kempton D , James L. Bailey A , Susan M. Wall B*

DOI: 10.12659/AJCR.932045

Am J Case Rep 2021; 22:e932045

Table 1. Laboratory values.

TestValueReference rangeHospital Day testedMembrane used when blood was sampled
White blood count11.9×10/ml4.2–9.1×10/ml1NA
Hemoglobin4.9 g/dL12.9–16.1 g/dL1NA
Platelet count209×10/ml150–400×10/ml1NA
Blood urea nitrogen166 mg/dL7–25 mg/dL1NA
Creatinine19.23 mg/dL0.7–1.30 mg/dL1NA
Potassium5.7 mmol/L3.5–5.0 mmol/L1NA
Carbon dioxide7 mmol/L23–29 mmol/L1NA
Phosphorus7.5 mg/dL2.5–5.0 mg/dL1NA
Peripheral smearNo schistocytes or blastsPSM
Activated partial thromboplastin time (s)27.525.1–36.59PSM
D dimer(ng/ml)21,531 ≤5749PSM
53,000 26PSM
31,000 40CTA
Fibrinogen activity (mg/dl)514 200–3939PSM
109 200–39326PSM
Folate (ng/ml)5.7>5.98PSM
Heparin-induced thrombocytopenia (HIT) panelNegative/0.122Negative ≤0.4999PSM
Hepatitis BNegative/0.88Negative ≤999.9910PSM
HIV antigen/antibody, HIV ODNegativeNegative25
Prothrombin time (s)14.7 9.4–12.57PSM
15.3 9PSM
13.5 12PSM
13.0 37PSM
Ristocetin cofactor (%)379 46–19631PSM
von Willebrand factor antigen (%)23253–27031PSM
Vitamin B12 (pg/ml)1474180–9148PSM
* Abnormal. PSM – polysulfone membrane; CTA – cellulose triacetate membrane; NA – not applicable.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923