02 August 2021
: Case report 
Acquired Thrombotic Thrombocytopenic Purpura Without Anti-ADAMTS13 Antibody Caused by Influenza A (H1N1) Virus Successfully Treated by Plasma Exchange: A Case Report
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Keisuke Kubo1ABDEF*, Tomohiro Abe
1ACDEF, Noriaki Kawano2B, Hidenobu Ochiai3ACEF
DOI: 10.12659/AJCR.932251
Am J Case Rep 2021; 22:e932251
Table 1. Laboratory findings on admission.
| Normal range | Day 1 | Day 8 | |
|---|---|---|---|
| White blood cell (×10/L) | 4.5–11.0 | 10.6 | 23.0 |
| Hemoglobin (mmol/L) | 120–155 | 121.0 | 91.0 |
| Mean corpuscular volume (fL) | 84.0–98.0 | 97.7 | 92.4 |
| Platelet (×10/µL) | 150–450 | 226 | 17.0 |
| Activated partial thromboplastin time (sec) | 25–40 | 42.8 | 23.2 |
| Prothrombin time-international normalized ratio | 0.90–1.10 | 0.83 | 0.96 |
| FDP (mg/L) | <5.0 | 69.1 | N/A |
| D-dimer(nmol/L) | <2.74 | 241.16 | N/A |
| Blood urea nitrogen (mol/L) | 2.9–8.2 | 17.06 | 18.99 |
| Creatinine (µmol/L) | 53–106 | 166.19 | 93.79 |
| Total bilirubin (µmol/L) | 2–18 | 0.64 | 20.18 |
| Aspartate aminotransferase (µkat/L) | 0.34–0.82 | 1.59 | 1.87 |
| Alanine aminotransferase (µkat/L) | <0.67 | 0.43 | 1.85 |
| Lactate dehydrogenase (µkat/L) | 1.72–3.38 | 15.97 | 44.27 |
| Creatinine kinase (µkat/L) | 0.85–3.40 | 7.97 | 4.69 |
| C-reactive protein (mg/L) | <2.0 | 254.7 | 16.30 |
| Procalcitonin (ng/mL) | <0.15 | 5.48 | N/A |
| FDP – fibrin degradation products. | |||