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09 September 2021: Articles

Giant Cell Carcinoma of the Endometrium: A Case Report of a Rare Entity with Aggressive Behavior

Challenging differential diagnosis, Rare disease

Maria Arafah A* , Raghad Adnan Bokhari A , Khalid Akkour B , Emadeddin Raddaoui A

DOI: 10.12659/AJCR.932916

Am J Case Rep 2021; 22:e932916

Table 1. Reported cases of giant cell carcinoma of the endometrium.

CaseAuthor, yearAge (years)Presentation% of giant cell componentPercentage of conventional cell typeFIGO stageReference
1Jones et al, 199143Vaginal bleeding15%Endometrioid (85%)IA[]4
2Jones et al, 199166Vaginal bleedingPredominantEndometrioidIA[]4
3Jones et al, 199164Vaginal bleedingPredominantEndometrioidIA[]4
4Jones et al, 199185Vaginal bleedingPredominantEndometrioidIIA[]4
5Jones et al, 199163Vaginal bleeding15%Endometrioid (85%)IVB[]4
6Jones et al, 199171Vaginal bleedingPredominantEndometrioidIVB[]4
7Mardi et al, 200870Vaginal bleedingPredominantEndometrioidIIIA[]5
8Mulligan et al, 201053Vaginal bleeding70%Clear cellIA[]6
9Mulligan et al, 201060Anemia100%Not presentIB[]6
10Mulligan et al, 201058Vaginal bleeding50%Endometrioid with spindle cellsIA[]6
11Mulligan et al, 201083Pelvic mass30%EndometrioidIIIC2[]6
12Mulligan et al, 201067Vaginal bleeding90%SerousIA[]6
13Bhattacharyya et al, 201270Vaginal bleeding80%EndometrioidIB[]7
14Sharma et al, 201660Vaginal bleeding60%EndometrioidIB[]8
15Ayık Aydın et al, 201975Vaginal bleedingNot availableNot availableIIIC[]9
16Current case71Vaginal bleeding>95%Not presentIACurrent case

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923