12 September 2021: Articles
An 11-Year-Old Saudi Arabian Girl Who Presented with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection with Coronary Artery Aneurysm and Cardiac Involvement: A Case Report
Unusual clinical course
Mohammed Al Qahtani C , Mohammed Shahab Uddin A* , Saleh Al fulayyih B , Sarah Al Baridi G , Zuhair Hamid FDOI: 10.12659/AJCR.933053
Am J Case Rep 2021; 22:e933053
Table 1. The results of laboratory testing for the first 172 h of hospitalization. Neutrophil counts were normal, lymphocytopenia and thrombocytopenia were present, and inflammatory markers, such as CRP, Procalcitonin, Ferritin, and high D-dimer, peaked at 96 h after the illness began. Normal prothrombin time (PT), partial thromboplastin time (aPTT), and international normalized ratio (INR).
| Lab test | Admission | 48 hrs | 96 hrs | 120 hrs. | 148 hrs | 172 hrs | Reference |
|---|---|---|---|---|---|---|---|
| WBC | 5.29 | 10.60 | 15.30 | 13.00 | 7.12 | 6.13 | 4–12×10/L |
| Neutrophil | 4.08 | 8.78 | 8.87 | 4.80 | 3.01 | 0.92 | 1.10–7.2×10/L |
| Lymphocyte | 0.55 | 0.40 | 0.64 | 1.14 | 1.28 | 3.17 | 1.30–7.20×10/L |
| Hb | 10.2 | 9.2 | 8.7 | 6.6 | 8.5 | 8.3 | 113–150 gm/L |
| Platelet | 199 | 108 | 114 | 99 | 129 | 143 | 150–400×10/L |
| CRP | 127.5 | 139.1 | 186.7 | 225.4 | 46.1 | 23.1 | (≤1.20 mg/L) |
| Procalcitonin | 2.13 | 12.7 | 24.8 | 36.1 | 21.9 | 11.6 | ≤0.05 ug/L (ng/mL) |
| ESR | 25 | 45 | 49 | 64 | 42 | 31 | 0–20 |
| Ferritin | 1313.9 | 4538.62 | 4543.0 | 1120.0 | 437.4 | 125.4 | 4.6–204 ug/L |
| LDH | 276 | 231 | 218 | X | 244 | X | 125–220 u/L |
| D-dimer | 4.02 | 3.21 | 4.59 | 3.1 | 2.4 | 1.7 | 0.00–0.50 mg/L |
| aPTT | 34.9 | 31.3 | 31.2 | 29.4 | 24.9 | 22.1 | 26.2–37.0 sec |
| PT | 11.6 | 9.5 | 10.9 | 14.4 | 9.8 | 9.9 | 7.6–10.4 sec |
| INR | 1.1 | 1.1 | 1.6 | 1.1 | X | 1.1 | 0.8–1.2 |
| Fibrinogen | 3.3 | X | 0.5 | 1.5 | X | 1.5 | 1.50–4.10 gm/L |
| Troponin | X | 48.3 | X | 29.3 | 23.4 | 17.9 | ≤15.6 pg/mL |
| Sodium | 130 | 130 | 132 | 134 | 133 | 135 | 138–145 mmol/L |
| Potassium | 3.4 | 3.6 | 3 | 3.8 | 3.5 | 4.1 | 3.4–4.7 mmol/L |
| Urea | 2.3 | 2 | 3 | 4.2 | 3.5 | 2.5 | 2.5–6.0 mmol/L |
| Creatinine | 52 | 39 | 40 | 46 | 40 | 45 | 27–62 umol/L |
| AST | 47 | 30 | 21 | 22 | X | 13 | 5–34 U/L |
| ALT | 33 | 41 | 32 | 24 | 27 | 25 | 5–55 U/L |
| Calcium | 2.05 | 1.84 | 1.74 | 1.89 | 2.03 | 2.14 | 2.20–2.70 mmol/L |
| Magnesium | 0.82 | 0.73 | 0.78 | 0.86 | 0.83 | 0.87 | 0.70–0.86 mmol/L |
| WBC – white blood cell; CRP – C-reactive protein; LDH – lactate dehydrogenase; AST – aspartate transaminase; ALT – alanine aminotransferase. | |||||||