25 November 2021
: Case report 
A Case of Paroxysmal Cold Hemoglobinuria Possessing Moderate Paroxysmal Nocturnal Hemoglobinuria-Type Erythrocytes
Challenging differential diagnosis
Takeshi Sugimoto1E*, Eri Masui2B, Shinya Ohata3B, Hideaki Goto1D, Takako Tomita2C, Hiromi Hashimoto2F, Yoshihiro Bouike4CDOI: 10.12659/AJCR.933102
Am J Case Rep 2021; 22:e933102
Table 1. The results of the serological test.
| Serological test | Result |
|---|---|
| Blood type | B type |
| Rh type | CcDEe |
| Antibody screening test (column technique) | (−) |
| Saline test (normal saline) | (−) |
| Saline test (cooled saline) | (+) |
| Antibody identification test | Anti-P1 |
| Direct antiglobulin test | |
| Broad spectrum | (−) |
| Anti-IgG | (−) |
| Anti-C3d | (−) |
| Indirect antiglobulin test | (−) |
| Donath-Landsteiner test | (+) |
| Cold agglutinin (titer) | 32 |
| Haptoglobin (mg/dL) | <10 |
| PNH-type cells | |
| Granulocytes | |
| Type III (%) | 73.0 |
| Type II+III (%) | 73.3 |
| Erythrocytes | |
| Type III (%) | 16.9 |
| Type II+III (%) | 19.6 |