13 August 2022: Articles
Interleukin-6 Is a Promising Marker of COVID-19 in Children: A Case Series of 2 Brothers with Severe COVID-19 Pneumonia
Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care
Maria Cristina Maggio A* , Maria Concetta Failla A , Salvatore Giordano A , Marco Pio La Manna B , Guido Sireci ADOI: 10.12659/AJCR.934468
Am J Case Rep 2022; 23:e934468
Table 1. Laboratory data during hospitalization.
| Case 1 (admission to hospital) | Case 1 (on discharge from the hospital) | Case 2 (admission to hospital) | Case 2 (on discharge from the hospital) | |
|---|---|---|---|---|
| Hemoglobin (g/dl) | 12.1 (n.v.: 10–13.5 g/dl) | 12 | 10.4 (n.v.: 10–13.5 g/dl) | 10.5 |
| Leukocytes (/µl) | 20290 (n.v.: 5200–8500/µl) | 9200 | 8020 (n.v.: 7900–13400/µl) | 6100 |
| Neutrophils (/µl) | 15330 (n.v.: 1900–8000/µl) | 5120 | 1520 (n.v.: 2600–7500/µl) | 1370 |
| Lymphocytes (/µl) | 3680 (n.v.: 900–5200/µl) | 2480 | 4750 (n.v.: 2300–5400/µl) | 4001 |
| NLR | 4.2 | 2.1 | 0.32 | 0.34 |
| Monocytes (/µl) | 1070 (160–1000/µl) | 1090 | 1130 (500–1900/µl) | 650 |
| Platelets (/µl) | 464000 (n.v.: 130000–400000/µl) | 455000 | 446000 (n.v.: 215000–448000/µl) | 528000 |
| CRP (n.v.: | 0.75 | 0.34 | 0.84 | 0.14 |
| ESR | 17 | 14 | 25 | 15 |
| Procalcitonin (n.v.: 0.02–0.05 ug/l) | 0.26 | 0.07 | ||
| Ferritin (n.v.: 28–365 ng/ml) | 29.5 | 28 | 28.5 | 27 |
| LDH (n.v.: 170–580 IU/l) | 310 | 299 | 263 | 300 |
| AST (n.v.: 15–55 IU/l) | 31 | 29 | 34 | 42 |
| ALT (n.v.: 5–41 IU/l) | 26 | 18 | 22 | 22 |
| Gamma-glutamyltransferase (5–32 IU/l) | 9 | 9 | 24 | 20 |
| Fibrinogen (200–400 mg/dl) | 350 | 344 | 310 | 280 |
| IL-6 (n.v. | 100.41 | 46.2 | ||
| Nasopharyngeal swab SARS-COV-2 | Positive | Negative | Positive | Negative |
| NLR – neutrophil-to-lymphocyte ratio; CRP – C-reactive protein; ESR – erythrocyte sedimentation rate; n.v. – normal value. | ||||