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13 August 2022: Articles

Interleukin-6 Is a Promising Marker of COVID-19 in Children: A Case Series of 2 Brothers with Severe COVID-19 Pneumonia

Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care

Maria Cristina Maggio A* , Maria Concetta Failla A , Salvatore Giordano A , Marco Pio La Manna B , Guido Sireci A

DOI: 10.12659/AJCR.934468

Am J Case Rep 2022; 23:e934468

Table 1. Laboratory data during hospitalization.

Case 1 (admission to hospital)Case 1 (on discharge from the hospital)Case 2 (admission to hospital)Case 2 (on discharge from the hospital)
Hemoglobin (g/dl)12.1 (n.v.: 10–13.5 g/dl)1210.4 (n.v.: 10–13.5 g/dl)10.5
Leukocytes (/µl)20290 (n.v.: 5200–8500/µl)92008020 (n.v.: 7900–13400/µl)6100
Neutrophils (/µl)15330 (n.v.: 1900–8000/µl)51201520 (n.v.: 2600–7500/µl)1370
Lymphocytes (/µl)3680 (n.v.: 900–5200/µl)24804750 (n.v.: 2300–5400/µl)4001
Monocytes (/µl)1070 (160–1000/µl)10901130 (500–1900/µl)650
Platelets (/µl)464000 (n.v.: 130000–400000/µl)455000446000 (n.v.: 215000–448000/µl)528000
CRP (n.v.:0.750.340.840.14
Procalcitonin (n.v.: 0.02–0.05 ug/l)0.260.07
Ferritin (n.v.: 28–365 ng/ml)29.52828.527
LDH (n.v.: 170–580 IU/l)310299263300
AST (n.v.: 15–55 IU/l)31293442
ALT (n.v.: 5–41 IU/l)26182222
Gamma-glutamyltransferase (5–32 IU/l)992420
Fibrinogen (200–400 mg/dl)350344310280
IL-6 (n.v.100.4146.2
Nasopharyngeal swab SARS-COV-2PositiveNegativePositiveNegative
NLR – neutrophil-to-lymphocyte ratio; CRP – C-reactive protein; ESR – erythrocyte sedimentation rate; n.v. – normal value.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923