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24 May 2022: Articles

A 62-Year-Old Man Presenting with Bilateral Tremor of the Upper Limb After a Diagnosis of COVID-19 with Confirmed Volumetric Brain Loss

Unusual clinical course, Challenging differential diagnosis

Sachin M. Bhagavan C* , Swathi Beladakere Ramaswamy D , Tejas R. Mehta E , Raghav Govindarajan A , Joseph Cousins C

DOI: 10.12659/AJCR.934955

Am J Case Rep 2022; 23:e934955

Table 1. Volumes of cerebral spinal fluid, white matter, the mesencephalon, third ventricle, and cerebellum calculated by Siemens Healthineers brain volumetric analysis, NeuroQuant, shows significant short-term increased cerebral spinal fluid and decreased white matter volume, indicating volume loss.

Volume (ml)Initial MRI2 months post COVID-19 MRImL difference% difference from initial exam
CSF358 ml392 ml34 ml9.5%
White matter507 ml471 ml36 ml7.1%
Mesencephalon9.8 ml9.7 ml0.1 ml1%
3 ventricle1.8 ml1.7 ml0.1 ml5.5%
Cerebellum103.1 ml104.5 ml1.4 ml0.013%
CSF – cerebrospinal fluid.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923