23 February 2022
: Case report 
Penile Necrosis Associated with Local Intravenous Injection of Cocaine
Challenging differential diagnosis, Rare disease
Haider Ghazanfar1ABCDEF*, Paola Valeria Espinosa1ABCDEF, Cosmina Zeana2ABCDEF, Sridhar Chilimuri1ABCDEF, Donald Rudikoff3ABCDEFDOI: 10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250
Table 1. Vasculitis and sexually transmitted disease workup.
| Investigation | Result |
|---|---|
| Human Immunodeficiency Virus (HIV) antibody | Negative |
| Urine Neisseria gonorrhoeae ribonucleic acid, transcription- mediated amplification (RNA, TMA) | Negative |
| Urine Chlamydia trachomatis RNA, TMA | Negative |
| Rapid plasma reagin (RPR) | Negative |
| Fluorescent treponemal antibody (FTA) | Negative |
| Hepatitis B core total antibody | Negative |
| Hepatitis B surface antibody | Positive |
| Hepatitis B surface antigen | Negative |
| Hepatitis C antibody | Positive |
| Hepatitis C viral load | Target not detected |
| Perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA) | Negative |
| Cytoplasmic antineutrophil cytoplasmic antibody (C-ANCA) | Negative |
| Cardiolipin antibody Immunoglobulin (Ig) G | <14 (≤14 ZZ) |
| Cardiolipin antibody IgA | <11 (≤11 ZZ) |
| Cardiolipin antibody IgM | <12 (≤12 ZZ) |
| B2-Glycoprotein I Ig A | 35 (≤20 ZZ) |
| B2-Glycoprotein I Ig M | 14 (≤20 ZZ) |
| B2-Glycoprotein I Ig G | 12 (≤20 ZZ) |
| Antiphosphatidylserine IGG antibody | <10 (<10 U/mL) |
| Antiphosphatidylserine IGM antibody | <25 (<25 U/mL) |
| Antiphosphatidylserine IGA antibody | <20 (<20 U/mL) |
| Urine drug screen | Positive for cannabis, cocaine, methadone |