Neuroleptic Malignant Syndrome with Adrenal Insufficiency After BNT162b2 COVID-19 Vaccination in a Man Taking Valproate: A
Case Report

06 May 2022 : Case report Japan

Unusual clinical course, Unexpected drug reaction

Tomohito Mizuno^1ABCDEF, Riku Takahashi^1BCD, Takahiro Kamiyama^1BCD, Atsushi Suzuki^1D, Masashi Suzuki^1ADE*

DOI: 10.12659/AJCR.936217

Am J Case Rep 2022; 23:e936217

Background Case Report Discussion Conclusions References:

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Table 2. Endocrinological data of the patient.

		Reference range
Thyroid-stimulating hormone (µIU/mL)	0.488	0.35–4.94
Free thyroxine (ng/dL)	0.79	0.70–1.48
Free triiodothyronine (pg/mL)	1.67	1.68–3.67
ACTH (pg/mL)	7.6	7.2–63.3
ACTH (250 μg) stimulation test
Cortisol (base) (µg/dL)	1.9	3.7–19.4
Cortisol 30 min (µg/dL)	4.4
Cortisol 60 min (µg/dL)	5.8
ACTH – adrenocorticotropic hormone.

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