Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

12 July 2022: Articles

Clinical Presentation of Serogroup 1-Associated Pneumonia and Diffuse Alveolar Hemorrhage: A Case Report and Literature Review

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Kazuhiro Ishikawa A* , Tomoaki Nakamura C , Takahiro Matsuo A , Fujimi Kawai F , Hinako Murakami B , Kotaro Aoki B , Tatsuya Nagasawa B , Yuki Uehara D , Nobuyoshi Mori A

DOI: 10.12659/AJCR.936309

Am J Case Rep 2022; 23:e936309

Supplementary Table 2. Clinical characteristics of previously reported cases of diffuse alveolar hemorrhage resulting from Legionella spp. infection.

ReferenceAgeSexPublication year/CountryUnderlying conditionAerosol exposureDiagnosis for AH/pathogen
1Chowdhur et al []7 67F2020/USACrohn’s disease on azathioprineN/ABAL/BAL PCR, culture
2Pataka et al []11 75M2018/GreeceHTNN/ABAL/urinary antigen
3Kashif et al []8 61M2017/USAHTN, DL, type 2 DM, obesityN/ABAL/urinary antigen
4Sundar and Pearce []9 57F2004/USAPCT, HCV, GERD, heavy smoking for 30 yearsN/ABAL/BAL PCR, culture, urinary antigen
5Marruchella and Franco []10 47F2003/ItalyMSN/ABAL/urinary antigen
6Present case44F2021/JapanSLE, SS, EBV retinitis and optic nephritis, on steroidYesBAL/BAL PCR, sputum culture
M – male; F – female; HTN – hypertension; type 2 DM – type 2 diabetes mellitus; SLE – systemic erythematous; SS – Sjögren’s syndrome; PCR – polymerase chain reaction; BAL – bronchoalveolar lavage; LVFX – levofloxacin; DOXY – doxycycline; AZM – azithromycin; SG – serogroup; PCT – porphyria cutanea tarda; HCV – hepatitis C; N/A – not applicable; MS – mitral valve stenosis; CAZ – ceftazidime; HTN – hypertension; MFLX – moxifloxacin; AH – alveolar hemorrhage; DL – dyslipidemia; PR3-ANCA – proteinase 3-antineutrophil cytoplasmic antibody.
ReferenceChief complaintSGABX for LegionellaSteroid useMechanical intubationPrognosis
1Chowdhur et al []7 Fever, appetite loss, fatigue, dizziness, cough3AZM, DOXY (AZM discontinued due to persistently prolonged QTc)YesYesCured
2Pataka et al []11 Fever, myalgia, dyspnea1MFLXYes/PR3-ANCA (+)YesUnresponsive to the treatment
3Kashif et al []8 Progressive dyspnea, acute cough, production of yellowish sputum, feverN/AAZM+LVFX for 21 daysYesYesCured
4Sundar and Pearce []9 Progressive dyspnea, fever, bloody sputumN/AAZMYesYesCured
5Marruchella and Franco []10 Fever, worsening dyspnea, pleuritic chest pain1CAM+RFPN/AYesCured
6Present caseDyspnea1LVFX for 14 daysYesNoCured
M – male; F – female; HTN – hypertension; type 2 DM – type 2 diabetes mellitus; SLE – systemic erythematous; SS – Sjögren’s syndrome; PCR – polymerase chain reaction; BAL – bronchoalveolar lavage; LVFX – levofloxacin; DOXY – doxycycline; AZM – azithromycin; SG – serogroup; PCT – porphyria cutanea tarda; HCV – hepatitis C; N/A – not applicable; MS – mitral valve stenosis; CAZ – ceftazidime; HTN – hypertension; MFLX – moxifloxacin; AH – alveolar hemorrhage; DL – dyslipidemia; PR3-ANCA – proteinase 3-antineutrophil cytoplasmic antibody.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923