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23 October 2022: Articles

A 60-Year-Old Woman with Primary Biliary Cholangitis and Crohn’s Ileitis Following the Suspension of Ursodeoxycholic Acid

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy , Educational Purpose (only if useful for a systematic review or synthesis)

Mario Romeo A , Marina Cipullo A , Giorgia Iadanza A , Simone Olivieri B , Antonietta Gerarda Gravina B , Raffaele Pellegrino B , Iacopo Panarese B , Marcello Dallio A* , Alessandro Federico A

DOI: 10.12659/AJCR.936387

Am J Case Rep 2022; 23:e936387

Table 1. Laboratory findings on admission.

Complete blood countBiochemical features
RBC (mm)4430000
Hb (g/dl)13.2
WBC (mm)3980
Neutrophils (mm)2000
Eosinophils (mm)100Creatinine (mg/dl)0.86
PLT (mm)217000Bilirubin (mg/dl)0.47
Total protein (g/dl)6.7
PT (%)104Albumin (g/dl)3.9
INR0.97Glucose (mg/dl)88
Fibrinogen (mg/dl)426
HDL cholesterol (mg/dl)59
CPK (U/l)18
AMANegativeNa (meq/l)140
ASMANegativeK (meq/l)4,1
APCANegativeIgG (mg/dl)982
Anti-TG-IgANegativeIgA (mg/dl)219
Anti-TG-IgGNegativeIgM (mg/dl)184
Anti-TGBNegativeFolic acid (ng/ml)6.7 (n.v. 3–16)
Anti-TPONegativeTransferrin (mg/dl)301
FT4 (pg/ml)8.2 (n.v. 5.2–15.8)ESR (mm/h)44 (n.v. 20)
TSH (microUI/ml)1.887 (n.v. 0.4–4.0)
Fecal calprotectinNegative
Bacterial and parasitological examinationNegative
NSE, chromogranin ANegative
RBC – red blood cell count; Hb – hemoglobin; WBC – white blood cell count; PLT – platelets; PT – prothrombin time; INR – International normalized ratio; ANA – antinuclear antibodies; AMA – antimitochondrial antibodies; ASMA – smooth muscle antibodies; TG – transglutaminase; EMA – anti-endomysium autoantibodies; TGB – thyroglobulin; TPO – thyroperoxidase; FT4 – free thyroxin 4; TSH – thyroid-stimulating hormone; AST – aspartate aminotransferase; ALT – alanine amino-transferase; Gamma-GT – gamma-glutamyl transferase; Ig – immunoglobulins; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; n.v. – normal value.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923