08 July 2022
: Case report 
Clinical Outcomes of Sotrovimab Treatment in 10 High-Risk Patients with Mild COVID-19: A Case Series
Unusual or unexpected effect of treatment
Kenichiro Takeda1ABCDEF*, Hajime Kasai1ABCDEF, Seiichiro Sakao1ABCDEF, Mikihito Saito1ABCDE, Kohei Shikano1ABCDEF, Akira Naito1ABDE, Mitsuhiro Abe1BE, Takeshi Kawasaki1ABCDEF, Misuzu Yahaba2ABCDEF, Toshibumi Taniguchi3ABCDEF, Hidetoshi Igari2ABCDEF, Takuji Suzuki1ABCDEFDOI: 10.12659/AJCR.936832
Am J Case Rep 2022; 23:e936832
Table 2. Results of blood examinations on admission.
| Case | No. of risk factors in blood examination | Lymphocytes (/μL) | Platelet (×103/μL) | D-dimer (μg/mL) | CRP (mg/dL) | PCT (ng/mL) | AST (U/L) |
|---|---|---|---|---|---|---|---|
| 1 | 2 | 1358 | 199 | 0.2 | 0.42 | 0.08 | 29 |
| 2 | 1 | 2448 | 142 | 0.4 | 0.05 | 0.03 | 40 |
| 3 | 4 | 637 | 157 | 0.3 | 0.75 | 0.08 | 48 |
| 4 | 2 | 558 | 233 | 0.6 | 0.73 | 0.06 | 16 |
| 5 | 7 | 464 | 140 | <0.1 | 1.64 | 2.78 | 10 |
| 6 | 4 | 512 | 192 | 0.8 | 0.36 | 0.19 | 26 |
| 7 | 4 | 594 | 147 | 0.9 | 0.28 | <0.02 | 21 |
| 8 | 3 | 840 | 242 | <0.1 | 0.82 | 0.02 | 59 |
| 9 | 3 | 1550 | 265 | 0.4 | 2.84 | 0.23 | 33 |
| 10 | 2 | 905 | 151 | 0.4 | 0.66 | 0.07 | 27 |
| ALT – alanine aminotransferase; AST – aspartate aminotransferase; CRP – C-reactive protein; IL-6 – interleukin-6; KL-6 – Krebs von den Lungen-6; LD – lactate dehydrogenase; PCT – procalcitonin. Cut-off values: Lymphocytes 1.0 mg/dL; PCT >0.5 ng/mL; AST >40 U/L; ALT >40 U/L; Creatinine >1.07 mg/dL; LD >222 U/L; Ferritin >500 μg/L []; IL-6 >55pg/mL []; KL-6 >406.5 U/mL []. | |||||||
| Case | No. of risk factors in blood examination | ALT (U/L) | Creatinine (mg/dL) | LD (U/L) | Ferritin (μg/L) | IL-6 (pg/mL) | KL-6 (U/mL) |
| 1 | 2 | 47 | 0.9 | 216 | 199 | 3.6 | 192 |
| 2 | 1 | 29 | 0.88 | 180 | 172 | 4.8 | 205 |
| 3 | 4 | 32 | 1.13 | 665 | 69 | 5.0 | 94 |
| 4 | 2 | 11 | 0.97 | 201 | 67 | 7.9 | 217 |
| 5 | 7 | 7 | 8.99 | 227 | 190 | 12.9 | 566 |
| 6 | 4 | 15 | 2.19 | 503 | 34 | 11.7 | 181 |
| 7 | 4 | 14 | 0.86 | 251 | 56 | 10.4 | 186 |
| 8 | 3 | 70 | 0.88 | 162 | 380 | 3.1 | 195 |
| 9 | 3 | 13 | 0.84 | 417 | 468 | 3.5 | 481 |
| 10 | 2 | 26 | 1.28 | 179 | 27.1 | 3.3 | 218 |
| ALT – alanine aminotransferase; AST – aspartate aminotransferase; CRP – C-reactive protein; IL-6 – interleukin-6; KL-6 – Krebs von den Lungen-6; LD – lactate dehydrogenase; PCT – procalcitonin. Cut-off values: Lymphocytes 1.0 mg/dL; PCT >0.5 ng/mL; AST >40 U/L; ALT >40 U/L; Creatinine >1.07 mg/dL; LD >222 U/L; Ferritin >500 μg/L []; IL-6 >55pg/mL []; KL-6 >406.5 U/mL []. | |||||||