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10 February 2023: Articles

Aleukemic Acute Promyelocytic Leukemia: How Concomitant HIV, Hepatitis C, and Chronic Alcohol Use Disorder May Have Hidden an Underlying Malignancy

Challenging differential diagnosis, Rare disease, Rare coexistence of disease or pathology

Anas Mahmoud A , Moutaz Ghrewati A , Brooke Kania A* , Minha Naseer A , Ashima Kapoor E , Patrick Michael A

DOI: 10.12659/AJCR.938086

Am J Case Rep 2023; 24:e938086

Table 1. Laboratory studies.

Laboratory studiesValues on admissionValues on dischargeReference range
  White blood cell count1.2×10/mm4.4×10/mm4.5–11.0
  Red blood cell count1.89×10/mm2.5×10/mm4.33–5.83
  Hemoglobin6.6 g/dL8.2 g/dL13.5–17.5
  Hematocrit19.5%24%41.0–53.0
  Mean corpuscular volume103.2 fL96.0 fL80.0–100.0
  Mean corpuscular hemoglobin34.9 pg32.8 pg26.0–32.0
  Mean corpuscular hemoglobin concentration33.8 g/dL34.2 g/dL31.0–37.0
  Red cell distribution width21.3%19.9%0.5–16.5
  Platelet count45 K/mm249 K/mm140–440
  Prothrombin time13.4 seconds12.2–14.9
  International normalized ratio1.0N/A
  Partial thromboplastin time28 seconds21.3–35.1
  Fibrinogen level289 mg/dL183–503
  Iron Level156 mcg/dL50–212
  Total iron binding capacity270 mcg/dL250–450
  Iron saturation58%15–50
  Ferritin level458 ng/mL16.4–294
  Folate level11 ng/mL≥4.1
  B12 level>1500 pg/mL211–911
  B-type natriuretic peptide587 pg/mL1–100
  Troponin-I17 pg/mL3–23
  Alcohol level≤10
  U Amphetamine ScrNegativeNegative
  U Barbiturate ScrNegativeNegative
  U Benzodiazapine ScrNegativeNegative
  U THC ScrPositiveNegative
  U Opiate ScrPositiveNegative
  U PCP ScrNegativeNegative
  HIV 1,2 Ag/Ab Combo548.71 s/coN/A
  HIV 1,2 Index≥1.00
  HIV 1,2 Ag/Ab InterpretationReactiveNon-reactive
  %CD4 Pos Lymph54.6%30.8–58.5
  %CD8 Pos Lymph33.4%12.0–35.5
  Abs CD4 Helper491/mcL359–1519
  Abs CD8 Suppressor301/mcL109–897
  HCV Ab> 11.0 s/co0.0–0.9
  HCV Load1890000
  Hep B Core IgM AbNegativeNegative
  Hep B Core Total AbPositiveNegative
  Hep B Surf AbNon-reactiveNon-reactive

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923