03 April 2023
: Case report 
A Case of Lupus Nephritis Preceded by Minimal Change Disease and Membranous Glomerulonephritis
Unusual clinical course, Mistake in diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents
Fengxia Zhang1A, Nan Jiang2BCDEF, Karthick Kumaran Munisamy Selvam1BCDEF, Bohou Li2BC, Qiong Wu2BC, Sichun Wen3BC, Ruiquan Xu4DEF*, Shuangxin Liu2AFGDOI: 10.12659/AJCR.938402
Am J Case Rep 2023; 24:e938402
Table 1. Pathological characteristics of the 3 renal biopsies.
| Parameters | First renal biopsy | Second renal biopsy | Third renal biopsy |
|---|---|---|---|
| Pathological diagnosis | Minimal change glomerulopathy | Membranous nephropathy (II period) | Membranous lupus nephritis |
| IgA in renal biopsy | Negative | negative | 2+, GCW and mesangium |
| IgG in renal biopsy | Negative | 3+, GCW | 3+, GCW and mesangium |
| IgM in renal biopsy | Negative | negative | 2+, GCW and mesangium |
| C3 in renal biopsy | Negative | 2+, GCW | 3+, GCW and mesangium |
| C1q in renal biopsy | Negative | 1–2+, GCW | 3+, GCW and mesangium |
| IgG1 in renal biopsy | ∼ | 2+, GCW | 3+, GCW and mesangium |
| IgG2 in renal biopsy | ∼ | ∼ | 2+, GCW and mesangium |
| IgG3 in renal biopsy | ∼ | ∼ | 2+, GCW and mesangium |
| IgG4 in renal biopsy | ∼ | 2+, GCW | – |
| κ in renal biopsy | ∼ | +− | +, GCW and mesangium |
| λ in renal biopsy | ∼ | + | +, GCW and mesangium |
| PLA2R in renal biopsy | ∼ | ∼ | – |
| GCW glomerular capillary walls’; “∼” specific laboratory test not done; “−” negative | |||