21 February 2023: Articles
Pharmacogenetic Testing in a 70-Year-Old Woman with Polypharmacy and Multiple Comorbidities: A Case Report
Unknown etiology, Adverse events of drug therapy
Jayson P. Jessop A , Joshua Russell A , Adriana DeJesus A , Chandni Bardolia A , Abeer Hanna B , Jacques Turgeon A* , Veronique Michaud A , Nishita S. Amin ADOI: 10.12659/AJCR.938850
Am J Case Rep 2023; 24:e938850
Table 3. Pharmacogenomic results.
| Gene | Result | Phenotype |
|---|---|---|
| CYP2C9 | *1|*2 | Intermediate metabolizer |
| CYP2C19 | *1|*1 | Normal metabolizer |
| CYP2D6 | *1|*4 | Intermediate metabolizer |
| CYP4F2 | *1|*3 | Reduced activity |
| SLCO1B1 (rs4149056) | *1B|*15 | Decreased function |
| VKORC1 (rs9923231) | A|A | Low activity |
| CYP – cytochrome P450. | ||