29 May 2023
: Case report 
A Rare Case of Primary Adrenal Epithelioid Angiosarcoma
Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Komson Wannasai
1ABCDEFG*, Puwitch Charoenchue 2BDF, Sunhawit Junrungsee3B, Chanakrit Boonplod 4BEF, Kornkanok Sukpan1D
DOI: 10.12659/AJCR.939397
Am J Case Rep 2023; 24:e939397
Table 2. Reported cases of primary adrenal epithelioid angiosarcoma.
| Author | Pub. Year | Age (y) | Sex | Side | Size (cm) | Presentation |
|---|---|---|---|---|---|---|
| Kareti et al []9 | 1988 | 54 | Male | Left | 6.0 | Left upper quadrant abdominal pain |
| Yang et al [] (1)6 | 2018 | 60 | Male | Left | 6.5 | High blood pressure |
| Yang et al [] (2)6 | 2018 | 60 | Male | Left | 8.0 | Severe pain in left lumbar region |
| Wei et al []10 | 2021 | 51 | Male | Left | 4.0 | Lower back pain |
| Livaditou et al []14 | 1991 | 59 | Male | Right | 7.0 | Right upper quadrant pain |
| Li et al []13 | 2017 | 59 | Male | Left | 5.4 | Left flank pain |
| Imran et al []19 | 2020 | 38 | Female | Right | 8.0 | Hemoptysis |
| Bosco et al []24 | 1991 | 54 | Female | Right | 6.0 | Fatigue |
| Croitoru et al []25 | 2001 | 63 | Male | Left | 3.0 | Incidental finding |
| Ben-Izhak et al []26 | 1992 | 41 | Male | Right | 10.0 | Epigastric discomfort |
| Lepoutre-Lussey et al []33 | 2012 | 35 | Male | Right | 6.0 | Polyuria and hypertension |
| Pasqual et al []21 | 2002 | 70 | Female | Right | 5.0 | Abdominal pain |
| Rodríguez-Pinilla et al []11 | 2002 | 61 | Male | Right | 12.0 | Abdominal pain |
| Criscuolo et al []12 | 2013 | 68 | Male | Left | 7.0 | Pain in left thorax |
| Antao et al []8 | 2019 | 58 | Male | Left | 17.5 | Left-sided abdominal pain |
| Sung et al []22 | 2013 | 42 | Male | Right | 14.0 | Right flank pain |
| N/A – data not available or no information in the article. | ||||||
| Author | Management | Chemotherapy | Radiotherapy | Outcome | ||
| Kareti et al []9 | Left adrenalectomy with en bloc resection | None | None | Free of tumor | ||
| Yang et al [] (1)6 | Laparoscopic left adrenalectomy | None | None | Alive | ||
| Yang et al [] (2)6 | Left adrenalectomy, left nephrectomy, and splenectomy | None | None | Died of disease | ||
| Wei et al []10 | Retroperitoneal laparoscopic resection of the left adrenal tumor | Liposomal doxorubicin and paclitaxel | None | Complete response | ||
| Livaditou et al []14 | Adrenalectomy with nephrectomy | None | None | Died 8 days after operation | ||
| Li et al []13 | Left laparoscopic adrenalectomy | N/A | N/A | Followup at 6 months after surgery | ||
| Imran et al []19 | Right adrenalectomy | Paclitaxel | N/A | Ongoing chemotherapy | ||
| Bosco et al []24 | Right adrenalectomy | N/A | N/A | No recurrence | ||
| Croitoru et al []25 | Left adrenalectomy | N/A | N/A | N/A | ||
| Ben-Izhak et al []26 | Laparotomy | N/A | Yes | Free of disease | ||
| Lepoutre-Lussey et al []33 | Right laparoscopic adrenalectomy | Adriamycin/ifosfamide | N/A | No recurrence | ||
| Pasqual et al []21 | Right adrenalectomy | None | N/A | No recurrence at 18 months after treatment | ||
| Rodríguez-Pinilla et al []11 | En bloc resection of tumor | None | None | No recurrence at 3 years after treatment | ||
| Criscuolo et al []12 | Laparoscopic ablation | Anthracycline | Yes | Died due to cachexia | ||
| Antao et al []8 | Left adrenalectomy, left nephrectomy, splenectomy, partial gastrectomy, and distal pancreatectomy | Paclitaxel, doxorubicin, carboplatin, etoposide-doxorubicin mitotane | N/A | Died due to disease progression and complications | ||
| Sung et al []22 | Right adrenalectomy and right nephrectomy | None | Yes | N/A | ||
| N/A – data not available or no information in the article. | ||||||