A Case of an 82-Year-Old Man with a Spinal Extradural Malignant Ossifying Fibromyxoid Tumor

23 May 2023: Articles

Challenging differential diagnosis, Rare disease

Qiqi Lu ^B* , Chi Long Ho ^A

DOI: 10.12659/AJCR.939408

Am J Case Rep 2023; 24:e939408

Table 1. Summary of previous cases of spinal ossifying fibromyxoid tumors (OFMT) reported in the literature.

First author, year (reference)	Age (year-old)/gender	Spinal involvement	Treatment	Prognosis
Cha (2008) []¹⁰	37/F	Locally aggressive, invaded L5 vertebra with epidural and pelvic/sacral extension	Pre-op arterial embolization, L5 vertebra corpectomy, subtotal tumor resection and posterior fusion	Post-op RT 25 fraction after surgery. No evidence of tumor recurrence over 5y follow-up
Jaypal (2010) []⁸	70/M	Paraspinal mass centred at L2 vertebra with epidural invasion via neural foramen	Tumor debulking followed by post-op RT 70 Gy	Remnant tumor enlarged 15-mths after debulking with paraspinal extension. Following second surgery, new recurrence after 4-mths. Patient refused further treatment
De Wandeler (2019) []⁹	37/F	Soft tissue mass centered at right trapezius muscle with extension to paraspinal muscles and central canal, compressing spinal cord and nerve roots	Surgical resection of primary tumor	Multiple recurrences were unsucessfully managed despite repeated surgery, RT and chemotherapy
Lu (2022) (current case)	82/M	Extradural tumor with cord compression	Tumor debulking followed by locoregional RT	Intracranial metastasis to cerebellopontine angles and ‘drop’ metastasis to the conus medullaris at 17-mths, and deceased 21-mths after initial tumor surgery
F – female; M – male; mth – months; RT – radiation therapy; y – years.