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26 May 2023 : Case report  USA

RLS-0071 Moderated Elevated Myeloperoxidase Level and Activity in an Asymptomatic Subject in Clinical Trial RLS-0071-101

Unknown etiology, Educational Purpose (only if useful for a systematic review or synthesis)

Jessica M. Goss1BCDF*, Pamela Hair1ABCDF, Parvathi S. Kumar1ADEF, Ulrich Thienel1AG, Kenji Cunnion1ACDEFG, Alexander Ellis2AE

DOI: 10.12659/AJCR.939803

Am J Case Rep 2023; 24:e939803

Table 3. Plasma myeloperoxidase (MPO) concentration and activity for subject 1504.

SampleMPO concentration (pmol/L)Analysis performed in duplicateMPO activity (pmol/min/ml) Analysis performed in triplicate
Mean (std error)Mean (std error)
Pre-dose 1142.0 (8.52)30.3 (5.34)
Pre-dose 980.8 (14.4)15.6 (1.02)
End-of-infusion dose 972.5 (28.0)11.5 (2.23)
1 hour after dose 974.7 (16.8)8.49 (1.90)
24 hours after dose 994.3 (19.4)13.6 (1.01)

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923