Pimavanserin Treatment for Psychosis in Patients with Dementia with Lewy Bodies: A Case Series

30 September 2023 : Case report USA

Unusual or unexpected effect of treatment

Kasia Gustaw Rothenberg^1ABDEF, Sharon G. McRae^23BE, Liza M. Dominguez-Colman^24BE, Andrew Shutes-David^23DEF, Debby W. Tsuang^24ABDE*

DOI: 10.12659/AJCR.939806

Am J Case Rep 2023; 24:e939806

Table 1. Summary of symptoms and medication responses for patients with DLB.

Patient #	Symptoms
	Dementia	Fluctuating cognition	Parkinsonian motor features	VHs	RBD	VH response to
	Dementia	Fluctuating cognition	Parkinsonian motor features	VHs	RBD	Cholinesterase inhibitors	Pimavanserin
1	+	+	+	+	+	No	Yes
2	+	+/–	+	+	+	No	Yes
3	+	+	+	+	+	Yes	No
4	+	+	+	+	+	No	Yes
+ indicates that the patient experienced the symptom; – indicates that the patient did not experience the symptom. RBD – rapid eye movement sleep behavior disorder; VH – visual hallucination.