24 October 2023
: Case report 
Episodic Cocaine Use as a Cause of Venous Thromboembolism and Acute Liver Injury
Unknown etiology
Khyati H. Patel1ABCDEF*, Kyle C. Thomas1ABCDE, Stephen K. Stacey2ABCDEDOI: 10.12659/AJCR.941360
Am J Case Rep 2023; 24:e941360
Table 1. Coagulation panel.
| Investigation | Day 1 | Day 2 | Day 9 | Day 10 | Day 13 | Day 14 |
|---|---|---|---|---|---|---|
| PT (11–13.5 s) | 17.4 | 16.1 | ||||
| aPTT (30–40 s) | 24 | 38 | ||||
| INR (<1.1) | 1.5 | 1.5 | 5.4 | 4.9 | 3.8 | 2.4 |
| D-dimer (<500 ng/mL) | 1445 | 1077 | ||||
| Fibrinogen (200–400 mg/dL) | 514 | |||||
| APCR ratio (>2.3) | 2.9 | |||||
| Antithrombin III (>50%) | 75% | |||||
| DRVVT Screen ratio (<1.2) | 1.04 | |||||
| Protein C | Normal | |||||
| Protein S | Normal | |||||
| Prothrombin G20210A | Negative | |||||
| Factor VIII (50–150%) | 35% | |||||
| TT (<20 s) | 64.6 | |||||
| PT – prothrombin time; aPTT – activated partial thromboplastin time; INR – international normalized ratio; APCR – activated protein C resistance; DRVVT – dilute Russell viper venom time (indicates lupus anticoagulant is not present); TT – thrombin time. | ||||||