07 December 2023
: Case report 
Immune-Mediated Non-Infectious Periaortitis After Aortic Graft Replacement Surgery: A Case Report Highlighting the Need for Immunosuppressive Therapy
Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care
Yuki Hiramatsu1ABCDEF, Eiji Hiraoka1ABCDEF*, Hikaru Ito1ABCDEF, Keiichi Iwanami2ABCDEF, Joji Ito3ABCDEF, Minoru Tabata34ABCDEFDOI: 10.12659/AJCR.941428
Am J Case Rep 2023; 24:e941428
Table 2. Cases of non-infectious inflammatory reaction (fever, elevated C-reactive protein, and peri-graft effusion) persisting for longer than 1 month.
| Patient | Age | Sex | Diagnosis | Graft product | Coating material | Body temperature* (degree Celsius) | Peak CRP level* (mg/dL) | Treatment | POD of Resolution of fever and elevated CRP | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 87 | Male | Aneurysm of common iliac artery | Hemashield | Collagen | 40.0 | 27.4 | Glucocorticoid | 10 months | 18 |
| 2 | 7 | Male | Ruptured aortic arch aneurysm secondary to Marfan syndrome | Hemashield | Collagen | 38.0 | 10.6 | No glucocorticoid | 31 days | 18 |
| 3 | 50 | Male | Dissection of ascending aorta to iliac artery | Gelweave | Gelatin | 38.6 | 2.1 | No glucocorticoid | 1 month | 17 |
| 4 | 73 | Male | Abdominal aortic aneurysm | Hemashield | Collagen | 38.8 | 18.0 | Glucocorticoid | 46 days | 20 |
| 5 | 49 | Male | Dissection of thoracic aorta to abdominal aorta | Gelweave and Triplex | Gelatin | 39.0 | 8.4 | Glucocorticoid | 6 months | (our case) |
| * The highest value described in the report; ** Peak C-reactive protein value in chronic phase after one month postoperatively. | ||||||||||