11 January 2024
: Case report
DRESS Syndrome: Renal Involvement in Two Cases – A Comprehensive Analysis and Literature Review of Improved Diagnosis and Treatment
Rare disease, Adverse events of drug therapy
Magdalena Natalia Mąsior1EF, Olga Maria Rostkowska


DOI: 10.12659/AJCR.942315
Am J Case Rep 2024; 25:e942315
Table 1. The Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) group diagnosis score for Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
No | Yes | Unknown | Case 1* | Case 2** | |
---|---|---|---|---|---|
≥ | −1 | 0 | −1 | −1 | −1 |
≥ | 0 | 1 | 0 | 0 | 0 |
0 | 1 | 0 | 0 | 0 | |
≥ ≥ | −1 | 1 | 0 | 2 | 2 |
≥ | 2 | ||||
−1 | 1 | 0 | 2 | 2 | |
≥ | 0 | 1 | 0 | ||
−1 | 0 | 0 | 0 | 1 | |
0 | 1 | ||||
2 | 1 | 2 | |||
≥ | −1 | 1 | −1 | 1 | 1 |
0 | 1 | 0 | 1 | 1 | |
(1 point if at least 3 of the following tests are performed and are negative: HAV, HBV, HCV, mycoplasma, chlamydia, ANA, blood culture) | |||||
Total score for DRESS diagnosis: * Case 1 – total of 6 points. ** Case 2 – total of 8 points. DRESS – Drug Reaction with Eosinophilia and Systemic Symptoms; HAV – hepatitis A virus; HBV – hepatitis B virus; HCV – hepatitis C virus; ANA – antinuclear antibodies. |