07 February 2024
: Case report 
Accelerating Healing and Relieving Pain: High-Intensity Laser Therapy for Paraneoplastic Cutaneous Vasculitis Associated with Multiple Myeloma
Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis)
Karina Felipe Fernandes Maciel1ABEF*, Antonio Henrique Cordeiro2B, Rivadavio Fernandes Batista de Amorim1ACDEF, Ludmila Bertti Coelho2F, Mariana de Freitas Cordeiro3ADE, Thiago David Alves Pinto1DOI: 10.12659/AJCR.942322
Am J Case Rep 2024; 25:e942322
Table 2. Features of the 22 patients with coexistent multiple myeloma and leukocytoclastic vasculitis and the related case.
| Reference | Age/sex | Biopsy site | Serum Ig secreted | Time | Follow-up |
|---|---|---|---|---|---|
| Bayer-Garner []4 | 58/M | Abdomen | IgA lambda | NA | |
| 67/F | Chest | Not available | NA | ||
| 42/F | Leg | IgA kappa | NA | ||
| 67/M | Abdomen | IgG kappa | NA | ||
| 57/M | Leg | IgG kappa | NA | ||
| 73/M | Arm | IgG kappa | NA | ||
| 66/M | Arm | IgG lambda | NA | ||
| 41/F | Leg | Not available | NA | ||
| Highet []15 | 44/M | Arms trunk | IgA lambda | 4 years before | Melphalan 5 mg + prednisone 40 mg |
| Raper []16 | 42/M | Arms | IgG lambda | Simultaneous | Prednisone cyclophosphamide plasma exchange |
| McMillen []17 | 58/F | Leg | IgA kappa | 3 years before | Melphalan, vincristine, cyclophosphamide, prednisone |
| Oymanns []18 | 58/M | Chest | IgG kappa | Simultaneous | No references |
| Oka []19 | 85/F | Leg | IgG kappa | Simultaneous | VRD regimen: bortezomib, lenalidomide, dexamethasone |
| Marini []20 | 50/F | Leg | IgG kappa | 12 years before | Transplant |
| Marini []20 | 72/M | Leg | IgG kappa | Weeks before | Dead |
| Kembre []14 | 52/M | Leg | Not available | 2 months before | Vincristine, Adriamycin, 50 mg prednisolone |
| 42/M | Arms | Not available | dead before | Finishing treatment | |
| Sánchez []21 | 73/F | Leg | IgG kappa | 1 year before | Melphalan, dexamethasone + prednisone, no response, dead |
| Abouzaid []22 | 48/F | Leg | IgA lambda | 4 years before | Vincristine, doxorubicin, dexamethasone |
| Jain []23 | 53/M | Leg | IgG kappa | months before | Vincristine, Adriamycin, dexamethasone, zoledronate |
| Lamaison []24 | 53/M | Leg | IgG kappa | Simultaneous | Cyclophosphamide, dexamethasone, bortezomib |
| Akpunonu []25 | 68/M | Leg | IgA kappa | Simultaneous | Melphalan12 mg + prednisone 80 mg |
| Our case | 76/F | Leg | IgG Kappa | Simultaneous | Prednisone |
| NA – not available; M – male; F – female. | |||||