25 January 2024
: Case report 
Lymphoscintigraphy and Single-Photon Emission Computed Tomography (SPECT)/CT to Determine Need for Second Sentinel Lymph Node Biopsy for Breast Cancer Recurrence Following Ipsilateral Breast/Axillary Surgery
Unusual clinical course, Challenging differential diagnosis
Satoko Nakano
1ABDEF*, Sayoko Kakimoto12DE, Saaya Takahashi13DE, Akemi Mibu 1BD, Hirokazu Saigusa 4BD
DOI: 10.12659/AJCR.942424
Am J Case Rep 2024; 25:e942424
Table 2. Summary of initial treatment, lymphoscintigraphy, and second surgery.
| Patient No. | Initial surgery | RT after the initial surgery | 15 min after radioisotope injection | 3 h after radioisotope injection | Surgery | Pathological results of SNB (Number of a metastasis in sentinel lymph nodes/number of lymph nodes extracted) |
|---|---|---|---|---|---|---|
| 1 | Bp+SNB | Done | Not detected | Ipsilateral internal mammary, ipsilateral intramammary and contralateral internal mammary > Ipsilateral axilla | Bt | Not done |
| 2 | SNB | Not done | Not detected | Not detected | Bt | Not done |
| 3 | Bp | Done | Ipsilateral axilla | Ipsilateral axilla | Bt+SNB | No metastasis (0/3) |
| 4 | Bp+SNB | Not done | Not detected | Ipsilateral axilla | Bp+SNB | No metastasis (0/2) |
| 5 | Bp+SNB | Done | Not detected | Ipsilateral axilla | Bt+SNB | No metastasis (0/3) |
| 6 | Bp+SNB | Done | Not detected | Ipsilateral internal mammary > contralateral axilla | Bt | Not done |
| 7 | Bp+SNB | Done | Ipsilateral internal mammary | Ipsilateral internal mammary > Ipsilateral axilla | Bt+SNB | No metastasis (0/1) |
| 8 | Bp+SNB | Done | Not detected | Ipsilateral internal mammary, subclavicular, contralateral axilla | Ax | Not done |
| 9 | Bp+SNB | Done | Not detected | Ipsilateral axilla, Ipsilateral internal mammary, contralateral axilla | Bt+SNB | No metastasis (0/1) |
| Bt – mastectomy; Bp – partial mastectomy; SNB – sentinel node biopsy; Ax – axillary dissection; RT – radiation therapy. | ||||||