02 April 2024: Articles
Hemorrhagic Presentation in Primary Central Nervous System Lymphoma: A Case Study
Unusual clinical course, Challenging differential diagnosis
Filipa Marques Rodrigues A* , Mariana Santos B , Ricardo Martins DDOI: 10.12659/AJCR.942951
Am J Case Rep 2024; 25:e942951
Table 1. Differential diagnosis of primary central nervous system lymphoma and typical imaging features.
| Differential diagnosis | Imaging features |
|---|---|
| Secondary central nervous system lymphoma | Indistinguishable; tends to involve leptomeninges |
| Glioma | Hemorrhage more common and centrally necrotic |
| Cerebral toxoplasmosis | Can be difficult; “concentric target sign” is suggestive |
| Cerebral abscess | “Dual rim sign” on susceptibility weighted imaging with thin peripheral enhancement and restricted diffusion in the center |