28 April 2024
: Case report
Contrast-Enhanced Ultrasonography in Diagnosing Intravascular Large B-Cell Lymphoma Infiltrating Liver Sinusoids
Challenging differential diagnosis, Rare disease
Hikari Ota1ABDEF*, Satoshi Nakayama2ABD, Hiroaki Takeo3BD, Sadahiro Watanabe4BD, Kazuhiro Masuoka1ADDOI: 10.12659/AJCR.943070
Am J Case Rep 2024; 25:e943070
Table 1. Cases of IVLBCL showing liver uptake on FDG-PET/CT [6,9,14–16].
| References | Age/Sex | Liver dysfunction | CT findings | FDG-PET/CT findings | CEUS findings | Biopsy site for diagnosis | Outcome |
|---|---|---|---|---|---|---|---|
| Shiiba []6 | 53/F | N.A. | Low density areas in liver and splenomegaly | Diffuse uptake in lungs and spleen, Multiple uptake lesions in liver | N.A. | Skin | Alive |
| Abe []9 | 72/F | No | No findings | Multiple uptake lesions in liver | Hypoenhan-cement in post-vascular phase | Liver | Alive |
| Steen []14 | 53/M | Yes | No findings | Diffuse uptake in liver | N.A. | Liver | Alive |
| Donald []15 | 60/M | N.A. | Hepatosple-nomegaly | Diffuse uptake in liver, spleen, bone marrow | N.A. | Bone marrow | N.A. |
| Li []16 | 65/M | Yes | Low density areas in liver | Multiple uptake lesions in liver | N.A. | Liver | Alive |
| Current case | 83/F | Yes | Low density areas in liver | Multiple uptake lesions in liver, bone marrow | Isoenhancement in post-vascular phase | Bone marrow | Died |
| IVLBCL –intravascular large B-cell lymphoma; FDG-PET – fluorodeoxyglucose positron emission tomography; CT – computed tomography; CEUS – contrast-enhanced ultrasonography, F – Female; N.A. – not available; M – Male. | |||||||






