Contrast-Enhanced Ultrasonography in Diagnosing Intravascular Large B-Cell Lymphoma Infiltrating Liver Sinusoids

28 April 2024: Articles

Challenging differential diagnosis, Rare disease

Hikari Ota ^A* , Satoshi Nakayama ^A , Hiroaki Takeo ^B , Sadahiro Watanabe ^B , Kazuhiro Masuoka ^A

DOI: 10.12659/AJCR.943070

Am J Case Rep 2024; 25:e943070

Table 1. Cases of IVLBCL showing liver uptake on FDG-PET/CT [6,9,14–16].

References	Age/Sex	Liver dysfunction	CT findings	FDG-PET/CT findings	CEUS findings	Biopsy site for diagnosis	Outcome
Shiiba []⁶	53/F	N.A.	Low density areas in liver and splenomegaly	Diffuse uptake in lungs and spleen, Multiple uptake lesions in liver	N.A.	Skin	Alive
Abe []⁹	72/F	No	No findings	Multiple uptake lesions in liver	Hypoenhan-cement in post-vascular phase	Liver	Alive
Steen []¹⁴	53/M	Yes	No findings	Diffuse uptake in liver	N.A.	Liver	Alive
Donald []¹⁵	60/M	N.A.	Hepatosple-nomegaly	Diffuse uptake in liver, spleen, bone marrow	N.A.	Bone marrow	N.A.
Li []¹⁶	65/M	Yes	Low density areas in liver	Multiple uptake lesions in liver	N.A.	Liver	Alive
Current case	83/F	Yes	Low density areas in liver	Multiple uptake lesions in liver, bone marrow	Isoenhancement in post-vascular phase	Bone marrow	Died
IVLBCL –intravascular large B-cell lymphoma; FDG-PET – fluorodeoxyglucose positron emission tomography; CT – computed tomography; CEUS – contrast-enhanced ultrasonography, F – Female; N.A. – not available; M – Male.