Successful Superficial Blood Sampling to Localize a Fibroblast Growth Factor-23-Producing Tumor

Junjiro Rikitake; Kenji Ashida; Ayako Nagayama; Yukihiro Inoguchi; Nao Hasuzawa; Masamichi Koganemaru; Tetsuya Hamada; Kanoko Moritaka; Mutsuyuki Demiya; Tomoki Sako; Jun Akiba; Koji Hiraoka; Masatoshi Nomura

doi:10.12659/AJCR.943152

13 April 2024 : Case report Japan

Successful Superficial Blood Sampling to Localize a Fibroblast Growth Factor-23-Producing Tumor

Challenging differential diagnosis, Unusual setting of medical care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Junjiro Rikitake^1ABCDEF, Kenji Ashida

^1ABCDEF*, Ayako Nagayama^1ACDEF, Yukihiro Inoguchi^1CDEF, Nao Hasuzawa^1CDEF, Masamichi Koganemaru^2BCDE, Tetsuya Hamada^3BCDE, Kanoko Moritaka^1BCDE, Mutsuyuki Demiya^1BCDE, Tomoki Sako^1BCDE, Jun Akiba^4BCDE, Koji Hiraoka^3BCDE, Masatoshi Nomura^1ACDEF

DOI: 10.12659/AJCR.943152

Am J Case Rep 2024; 25:e943152

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Introduction Case Report Discussion Conclusions References:

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Table 1. Laboratory data on admission.

Parameters	Values	Reference range

Protein, mg/dL		Negative

Total protein, g/dL	6.6	6.6–8.1
Albumin, g/dL		4.1–5.1
BUN, mg/dL	16	8–20
Cre, mg/dL	0.87	0.65–1.07
Uric acid, mg/dL	5.6	3.7–7.0

Sodium, mmol/L	141	138–145
Potassium, mmol/L	4.2	3.6–4.8
Chloride, mmol/L	106	101–108

FPG, mg/dL	91	70–109

CRP, mg/dL

Intact-PTH, pg/mL	40.9	10.0–65.0
Intact FGF-23, pg/mL		19.9–52.9
1,25 (OH) D, pg/mL	24.2	20.0–60.0
25 (OH) D, ng/mL		≥30
Total P1NP, ng/mL		18.1–74.1
Occult blood	–	Negative
AST, IU/L	24	13–30
ALT, IU/L	23	10–30
ALP, U/L		38–113
CK, IU/L	86	59–248
LDL-cholesterol, mg/dL	116	65–139
Calcium, mg/dL	8.7	8.8–10.1
Phosphate, mg/dL		2.7–4.6
HbA1c (NGSP), %	5.8	4.9–6.0
TSH, μU/mL	0.870	0.500–5.000
Free thyroxine, ng/dL	1.16	0.93–1.70
Free thyronine, pg/mL	2.9	2.3–4.0
TRACP-5b, mU/dL		170–590
^* Reference range that is supposed to be sufficient with vitamin D. CK – creatine kinase; Cre – creatinine; DEX – dexamethasone; FPG – fasting plasma glucose; HbA1c – hemoglobin A1c; CRP – C-reactive protein; P1NP – procollagen type 1 N-terminal propeptide; TRACP-5b – tartrate-resistant acid phosphatase 5b; TSH – thyroid-stimulating hormone; PTH – parathyroid hormone; BUN – blood urea nitrogen; AST – aspartate aminotransferase; ALT – alanine aminotransferase; LDL – low-density lipoprotein.

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Successful Superficial Blood Sampling to Localize a Fibroblast Growth Factor-23-Producing Tumor

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