13 April 2024: Articles
Successful Superficial Blood Sampling to Localize a Fibroblast Growth Factor-23-Producing Tumor
Challenging differential diagnosis, Unusual setting of medical care, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Junjiro Rikitake A , Kenji Ashida A* , Ayako Nagayama A , Yukihiro Inoguchi C , Nao Hasuzawa C , Masamichi Koganemaru B , Tetsuya Hamada B , Kanoko Moritaka B , Mutsuyuki Demiya B , Tomoki Sako B , Jun Akiba B , Koji Hiraoka B , Masatoshi Nomura ADOI: 10.12659/AJCR.943152
Am J Case Rep 2024; 25:e943152
Table 2. Examination of blood sampling methods from review of literature.
| ACTH | Inferior petrosal sinus sampling | Prolactin | (With CRH stimulation) Central/Peripheral ratio ≥3 indicates central production (Without CRH stimulation) Central/Peripheral ratio ≥2 indicates central production | [,]7 |
| Intact-PTH | None | Elevation in the intact-PTH level by ≥2 times than that in other peripheral veins indicates the drainage vein | []14 | |
| Insulin | Selective arterial secretagogue injection (SASI) test | None | (Rapid gluconate calcium injection via branches of the celiac artery [gastroduodenal; splenic; and superior mesenteric arteries]) The substantial increase, after calcium injection, indicates the feeding artery of the insulinoma | []9 |
| Gastrin | Selective arterial secretagogue injection (SASI) test | None | (Rapid gluconate calcium injection via branches of the celiac artery [gastroduodenal; splenic; and superior mesenteric arteries]) The elevations in the gastrin level at either 20 or 40 s (>80 pg/mL and >20% from the basal level) indicate the feeding artery of the gastrinoma. | []22 |
| Aldosterone | Cortisol | (Mostly with intravenous administration of ACTH) The (aldosterone/cortisol) values are used for the following investigations: | [,, ,]10 | |
| Testosterone | None | The sampling vein that shows the highest level is considered as the drainage vein A peripheral testosterone value ≥4.51 nmol/L (≥130 ng/dL) and R: L ovarian testosterone ratio ≥1.44 | [,]12 | |
| Progesterone | None | The sampling vein exhibiting step-up of progesterone is considered as responsible site | []13 | |
| FGF-23 | • Principal veins (13 or 22 points) were listed for systemic exploration for detecting responsible tumor | None | The sampling point that shows discernibly elevated FGF-23 level indicates the presence of FGF-23-producing tumor in its distal region | [,, –]4 |
| FGF-23 – fibroblast growth factor-23; ACTH – adrenocorticotropic hormone; PTH – parathyroid hormone; CT – computed tomography; MRI – magnetic resonance imaging. | ||||