23 May 2024
: Case report
Duodenal Soft Tissue Sarcoma with GLI1 Gene Rearrangement: A Case Report and Literature Review
Rare disease
Jinghe Li
DOI: 10.12659/AJCR.943271
Am J Case Rep 2024; 25:e943271
Table 3. Publication year and main clinical features of previously published cases.
Study | Locations | Type of GLI1 gene rearrangement | Treatment | Postoperative adjuvant therapy |
---|---|---|---|---|
Antonescu CR et al 2018 []14 | 6 Cases: Thigh, foot, retroperitoneum, chest wall, neck, bone | Fusion: ACTB-GLI1, MALAT1-GLI, PTCH1-GLI1 | Operation | Observation: 1case AWD at 20 months; 1 case AWD at 80 months |
Prall OWJ et al 2020 []3 | Jejunum | Fusion: MALAT1-GLI1 | Operation | Immunotherapy: 26-year survival History |
Bridge JA et al 2012 []4 | Bone | Fusion: ACTB-GLI1 | Operation | No follow-up data |
Lopez-Nunez O et al 2020 []16 | Thigh | Fusion: APOD-GLI1 | Operation | No follow-up data |
Agaram NP et al 2019 []5 | 10 Cases: Thigh, shoulder, elbow, forearm, finger, back, neck, tongue, and lung | Amplification: Co-amplification of genes CDK4 and MDM2 | Operation | Observation: 1 case AWD at 26 months; 1 case alive NED at 16 months |
Jessurun J et al 2022 []2 | Case 1: Terminal ileumCase 2: DuodenumCase 3: Jejunum | Case 1: DDIT3-GLI1Case 2: AARS- GLI1Case 3: ACTB-GLI1 | Operation | Observation: Alive NED after surgical resection (3y, 12y, 1y) |
NED – no evidence of disease. AWD – alive with disease. # There is no follow-up data for other cases. |