Logo American Journal of Case Reports

Call: 1.631.629.4328
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo American Journal of Case Reports Logo American Journal of Case Reports Logo American Journal of Case Reports

22 June 2024 : Case report  Jordan

Blue Toe Syndrome in Behçet’s Disease: A Case Report

Unusual clinical course, Challenging differential diagnosis

Qusai Aljarrah ORCID logo1AF*, Saleh A. Ba-shammakh2DEF, Mohammed Z. Allouh ORCID logo23EF, Mohammed W. Afaneh1ABDEF

DOI: 10.12659/AJCR.943813

Am J Case Rep 2024; 25:e943813

Table 1. Blue toe syndrome differential diagnosis.

Blue toe syndromeRaynaud’s phenomenon [33-36]
EtiologyAuto-inflammatory/autoimmuneStress/cold exposure
PathogenesisVasculitisVasospasm
Structural changesMicro- or macro-vascular structural changesNone
Vessels affectedSmall arteries proximal to digital arteriesDigital arteries
SymmetryMore often AsymmetricMore often Symmetric
SeverityMore severeLess severe
CourseUsually progressiveUsually recurrent
Inflammatory markersElevatedNormal
Signs and symptomsPain and gangrenePain and triple-color change
TreatmentAnti-inflammatories, anti-coagulants, anti-platelets, vasodilatorsUsually self-limiting; vasodilators, anti-platelets

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923