Blue Toe Syndrome in Behçet’s Disease: A Case Report

22 June 2024 : Case report Jordan

Unusual clinical course, Challenging differential diagnosis

Qusai Aljarrah

^1AF*, Saleh A. Ba-shammakh^2DEF, Mohammed Z. Allouh

^23EF, Mohammed W. Afaneh^1ABDEF

DOI: 10.12659/AJCR.943813

Am J Case Rep 2024; 25:e943813

Introduction Case Report Discussion Conclusions References:

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Table 1. Blue toe syndrome differential diagnosis.

	Blue toe syndrome	Raynaud’s phenomenon [33-36]
Etiology	Auto-inflammatory/autoimmune	Stress/cold exposure
Pathogenesis	Vasculitis	Vasospasm
Structural changes	Micro- or macro-vascular structural changes	None
Vessels affected	Small arteries proximal to digital arteries	Digital arteries
Symmetry	More often Asymmetric	More often Symmetric
Severity	More severe	Less severe
Course	Usually progressive	Usually recurrent
Inflammatory markers	Elevated	Normal
Signs and symptoms	Pain and gangrene	Pain and triple-color change
Treatment	Anti-inflammatories, anti-coagulants, anti-platelets, vasodilators	Usually self-limiting; vasodilators, anti-platelets

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