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17 June 2024 : Case report  China (mainland)

Genome Sequencing Analysis of a Rare Case of Blood Infection Caused by Flavonifractor plautii

Challenging differential diagnosis, Management of emergency care, Patient complains / malpractice, Unexpected drug reaction, Rare disease, Clinical situation which can not be reproduced for ethical reasons

Xingying Chen1ABCD, Wei Bi1ABCDE, Xinyi Ruan2AB, Limin Jin1ABEFG, Nenghua Zhang1ABCDEFG*

DOI: 10.12659/AJCR.943920

Am J Case Rep 2024; 25:e943920

Table 1. Drug sensitivity test results of Flavonifractor plautii.

SubstanceMIC (μg/L)Breakpoint range in μg/L (CLSI)
Penicillin0.50S(0.5–2)
Ampicillin0.50S(0.5–2)
Piperacillin tazobactam2/4S(16/4–128/4)
Cefatriaxone0.50–1.00S(16–64)
Imipenem0.12S(4–16)
Meropenem<0.01S(4–16)
Tetracycline32.00R (4–16)
Ciprofloxacin>32.00R(2–8)
Levofloxacin8.00R(2–8)
Clindamycin0.25S(2–8)
Chloramphenicol2.00S(8–32)
Metronidazole<0.01S(8–32)
* CLSI breakpoints for gram-positive anaerobes are utilized;
# CLSI non-species-related breakpoints are utilized. CLSI is the abbreviation of Clinical and Laboratory Standards Institute.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923