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26 September 2024 : Case report  Japan

Refractory Iron-Deficiency Anemia and Vascular Malformation Concomitant with Aortic Stenosis: Heyde Syndrome

Challenging differential diagnosis, Rare disease

Risa Hirata1AEF, Tomoyo Nishi1AE, Masahiko Nakamura1AE, Masaki Tago1AEF*

DOI: 10.12659/AJCR.944440

Am J Case Rep 2024; 25:e944440

Table 1. Laboratory findings on admission.

AST200nkat/L167–667
White blood cells6.410/L3.9–9.8ALT133nkat/L83–667
Neutrophil69.6%γ-GTP0.1µkat/L≤0.5
Lymphocyte23.6%LDH3.62µkat/L2.07–3.70
Red blood cells1.5310/L4.10–5.30ALP0.87µkat/L0.63–1.88
Hemoglobin41g/L135–176Amylase1.38µkat/L0.62–2.08
Hematocrit0.14L/L0.36–0.48CK1.05µkat/L0.75–2.72
MCV93.5fL80–100Na138mmol/L138–146
Platelets12310/L86–123K4.6mmol/L3.6–4.9
Cl106mmol/L99–109
PT-INR0.99Ca2.05mmol/L2.12–2.54
APTT24.2s24.3–36.0CRP3.8nmol/L<13.3
Fibrinogen2.82g/L1.50–3.00
D-dimer1.1mg/L<1.0NT-pro BNP183.2pmol/L≤14.8
Fe3.6µmol/L8.60–27.6
TP60g/L67–83TIBC72.7µmol/L44.1–73.4
Albumin36g/L38–50UIBC69.1µmol/L19.3–58.2
BUN8.61mmol/L2.86–7.86Ferritin38.2pmol/L8.1–256.2
Cr96.4µmol/L41.5–69.8Vitamin B129.9pmol/L132.8–674.4
T-Bil8.6µmol/L5.13–20.5Folic acid14.3nmol/L>9.1
Glucose6.72mmol/L3.89–6.05
ALP– alkaline phosphatase; ALT – alanine aminotransferase; APTT – activated partial thromboplastin time; AST – aspartate aminotransferase; BUN – blood urea nitrogen; Ca – calcium; CK – creatine kinase; Cl – chloride; Cr – creatinine; CRP – C-reactive protein; Fe – iron; K – potassium; LDH – lactate dehydrogenase; MCV – mean corpuscular volume; NA – sodium; NT-proBNP – N-terminal prohormone of brain natriuretic peptide; PT-INR – prothrombin time – international normalized ratio; T-Bil – total bilirubin; TIBC – total iron binding capacity; TP – total protein; UIBC – unsaturated iron binding capacity; γ-GTP – gamma-glutamyl transpeptidase.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923