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16 October 2024 : Case report  Belgium

Late-Onset Hemophagocytic Lymphohistiocytosis in a Lung Transplant Patient: A Case of T-Cell Post-Transplant Lymphoproliferative Disorder

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Rare disease

Charline Leclercq1BEF, Pierre-Yves Sansen2DE, Elodie Collinge2BE, Robin Thirionet1BE, Patrick Evrard3E, Thomas Planté-Bordeneuve13E, Caroline Fervaille4B, Marie Pouplard5B, Michel Dumonceaux13E, Anne Sonet2E, François M. Carlier ORCID logo13ABCDEG*

DOI: 10.12659/AJCR.944761

Am J Case Rep 2024; 25:e944761

Table 1. Main biological values at admission.

ReadoutValueUnitReference values
  Hemoglobin8.8g/dL12.0–15.8
  Red blood cells2,590×10/µL3500–5300×10
  Hematocrit26.3%33.0–46.0
  Mean corpuscle volume101.5µm80.1–99.8
  Leukocytes680×10/µL3,900–11,100×10
  Neutrophils530×10/µL2,100–7,500×10
  Lymphocytes20×10/µL1000–3000×10
  Monocytes130×10/µL0.240–0.910×10
  Platelets50×10/µL150–400×10
  Reticulocytes29×10/µL25.0–75.0×10
  Schistocytes0.33%<0.5%
  Natrium129mmol/L137–145
  Potassium4.6mmol/L3.5–5.1
  Chloride106mmol/L98–107
  Bicarbonate14mmol/L22–30
  Calcium2.16mmol/L2.10–2.55
  Magnesium0.54mmol/L0.66–0.94
  Creatinine2.76mg/dL0.52–1.04
  Urea99mg/dL15–36
  Estimated glomerular flow rate18.2mL/min/1.73m
  Total proteins51.0g/L63.0–82.0
  Albumin31.7g/L35.0–50.0
  Total bilirubin0.55mg/dL0.00–1.30
  Haptoglobin1.28g/L0.34–2.00
  Ferritin724.0µg/L11.1–264.0
  Fibrinogen398mg/dL180–400
  LDH241IU/L120–246
  Alkaline phosphatases60IU/L38–126
  Aspartate transaminase16IU/L14–36
  Alanine transaminase11IU/L<35
  Gamma-GT10IU/L12–43
  Creatine phosphokinase<20IU/L30–135
  Triglycerides286mg/dL<150
  Tacrolimus9.40ng/mL8–10

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923