28 December 2024
: Case report 
Role of Renal Replacement Therapy in Managing Toluene-Induced Acidosis
Challenging differential diagnosis, Management of emergency care, Rare disease, Rare coexistence of disease or pathology
Norihito Yoshida
ABCDEF 1*, Sadamu Takahashi B 1, Mai Hitaka B 1, Yasushi Ohashi DE 1, Ryo Ichibayashi CDE 2
DOI: 10.12659/AJCR.945657
Am J Case Rep 2024; 25:e945657
Table 1. Blood and urinary test results.
| Results | Standard ranges | |
|---|---|---|
| White blood cell | 8380/μl | 3300–9000/μl |
| Hemoglobin | 12.5 g/dl | 13.5–17.5 g/dl |
| Platelets | 22.0×10 μl | 14–34×10 μl |
| CRP | 0.86 mg/dL | ≤0.30 mg/dl |
| TP | 9.1 g/dL | 6.7–8.3 g/dl |
| Albumin | 5.3 g/dL | 3.8–5.2 g/dl |
| AST | 46 IU/L | 10–40 IU/L |
| ALT | 25 IU/L | 5–45 IU/L |
| LDH | 454 U/L | 124–222 U/L |
| γ-GTP | 18 IU/L | ≤80 IU/L |
| Creatine kinase | 420 mg/dL | 60–270 IU/L |
| Sodium (Na) | 140 mEq/L | 137–147 mEq/L |
| Potassium (K) | 4.7 mEq/L | 3.5–5.0 mEq/L |
| Chloride (Cl) | 102 mEq/L | 98–108 mEq/L |
| BUN | 24.2 mg/dL | 8–20 mg/dl |
| Creatinine | 1.48 mg/dL | 0.61–1.04 mg/dL |
| Calcium (Ca) | 9.5 mg/dL | 8.4–10.4 mg/dL |
| Phosphorus (P) | 6.8 mg/dL | 2.5–4.5 mg/dL |
| Blood glucose | 106 mg/dL | 73–109 mg/dL |
| Osmolality gap | 4 mOsm/kg·HO | 0–10 mOsm/kg·HO |
| HbA1c | 5.2% | 4.6–6.2 (NGSP)% |
| pH | 7.296 | 7.350–7.450 |
| HCO3 | 7.6 mmol/L | 20.0–26.0 mmol/L |
| BE | −19.9 mmol/L | −3.0–3.0 mmol/L |
| Lactate | 1.15 mmol/L | 0.44–1.78 mmol/L |
| Blood AG | 30.4 mmol/L | 10–14 mmol/L |
| Corrected HCO3 | 26 mmol/L | 20.0–26.0 mmol/L |
| pH | 5.5 | 5.0–8.0 |
| Specific gravity | 1.014 | 1.005–1.030 |
| Urinary AG | 75.9 mEq/L | N/A |
| Osmolality gap | 40 mmOsml/L | N/A |
| NAG | 4.2 U/L | 0.7–11.2 IU/L |
| β2MG | 125 μg/gCr | <200/μg/L |
| L-FABP | 189 μg/gCr | <8.4 μg/gCr |
| NGAL | 321 μg/gCr | <21.7μg/gCr |
| Aminoaciduria | negative | negative |
| Hippuric acid | 3.78 g/L | ≤0.01 g/L |
| Methyl uric acid | ≤0.01 g/L | ≤0.01 g/L |
| CRP – C-reactive protein; TP – total protein; AG – anion gap; Alb – albumin; AST – aspartate aminotransferase; ALT – alanine aminotransferase; LDH – lactate dehydrogenase; γ-GTP – γ-glutamyl transpeptidase; T-Bil – total bilirubin; BUN – blood urea nitrogen; eGFR – estimated glomerular filtration; HbA1c – hemoglobin A1c; WBC – white blood cell; RBC – red blood cell; Hb – hemoglobin; Ht – hematocrit; Plt – platelet; BE – base excess; NAG – N-acetyl-β-D-glucosaminidase; β2MG – β2-microglobulin; L-FABP – L-type fatty acid-binding protein; NGAL – neutrophil gelatinase-associated lipocalin; NGSP – National Glycohemoglobin Standardization Program. | ||