04 January 2025
: Case report 
Negative-Pressure Wound Therapy: A Novel Approach for Terminal Ileum Anastomosis Success
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
María J. Pérez-Restrepo
ABDEF 1,2, Carlos A. Moya-Ortiz ABDEF 1,2, Sara Eslait-Olaciregui ABDEF 1,2*, Dayana K. Báez-López ABDEF 1, Nathaly Páez ABDEF 1,2, Diego A. Piñeros Nieto ABDEF 3, Carlos F. Román Ortega ABDEF 1, Jorge Alejandro Gonzalez ABCEF 1, Paulo A. Cabrera Rivera ABDEF 1
DOI: 10.12659/AJCR.945745
Am J Case Rep 2025; 26:e945745
Table 1. Main characteristics of the patients.
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| Age | 65 years | 73 years | 69 years |
| Sex | Female | Male | Male |
| Reason for the resection | Mesenteric ischemia | Intestinal obstruction (dehiscence of anastomosis previously made by incarcerated inguinal herniorrhaphy) | Mesenteric ischemia |
| Type of anastomosis | End-to-side anastomosis in 2 planes | Side-to-side anastomosis in 2 planes | End-to-end anastomosis in 2 planes |
| Distance between the anastomosis and ileocecal valve | 10 cm | 15 cm | 12 cm |
| NPT configuration | First stage: VAC at a pressure of −75 mmHg for 2 daysSecond stage: VAC at a pressure of −125 mmHg for 6 days | First stage: −100 mmHg for 2 daysSecond stage: −50 mmHg for 3 days | VAC at −50 mmHg, medium intensity, continuous |
| Total NPT time | 8 days | 5 days | 4 days |
| NPT – negative-pressure therapy; VAC – vacuum-assisted closure. | |||