07 January 2025
: Case report 
Pediatric Mycosis Fungoides Mimicking Benign Dermatoses: A Report of a Rare Case
Challenging differential diagnosis, Rare disease
Salwa Rosli EF 1, Haizlene Abd Halim E 1,2*, Mazapuspavina Md-Yasin E 1,2, Nur Aini Abu Bakar E 3DOI: 10.12659/AJCR.945897
Am J Case Rep 2025; 26:e945897
Table 1. European Organisation for Research and Treatment of Cancer (EORTC) Classification of mycosis fungoides (MF) [11].
| TNMB stages | |
|---|---|
| T | Patches, papules, and/or plaques covering <10% of the skin surface |
| T | Patch only |
| T | Plaque and patch |
| T | Patches, papules or plaques covering ≥10% of the skin surface |
| T | Patch only |
| T | Plaque and patch |
| T | One or more tumors (1 cm diameter) |
| N | No clinically abnormal peripheral lymph nodes; biopsy not required |
| N | Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN |
| N | Clone negative |
| N | Clone positive |
| N | Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN |
| N | Clone negative |
| N | Clone positive |
| N | Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative |
| N | Clinically abnormal peripheral lymph nodes; no histologic confirmation |
| M | No visceral involvement |
| M | Visceral involvement |
| B | Absence of significant blood involvement: 5% of peripheral blood lymphocytes are atypical Sézary cells |
| B | Clone negative |
| B | Clone positive |
| B | Low blood tumor burden: 5% of peripheral blood lymphocytes are atypical Sézary cells but does not meet the criteria of B |
| B | Clone negative |
| B | Clone positive |
| B | High blood tumor burden: 1000/L Sézary cells with positive clone |
| TNMB – Tumor, Node, Metastasis, Blood classification stage; NCI – National Cancer Institute; LN – lymph node. | |