09 March 2025
: Case report 
A 58-Year-Old Man with a History of Autoimmune Thyroiditis Diagnosed with Mucosa-Associated Lymphoid Tissue Lymphoma and Papillary Carcinoma of the Thyroid
Challenging differential diagnosis, Rare disease
Naru Babaya
ABCDEF 1*, Sawa Yoshida ABCD 1, Shinsuke Noso D 1, Yoshihisa Hiromine D 1, Yasunori Taketomo D 1, Takayuki Kimura BD 2, Hiroaki Kakutani BD 3, Takao Satou BD 4, Hiroshi Ikegami DE 1, Norikazu Maeda DE 1
DOI: 10.12659/AJCR.946022
Am J Case Rep 2025; 26:e946022
Table 1. Laboratory findings of the patient.
| WBC | 6790/mm | (3300–8600) | Total protein | 8.0 g/dL | (6.6–8.1) |
| Neutrophils | 79.4% | (38–77) | Albumin | 4.2 g/dL | (4.1–5.1) |
| Lymphocytes | 14.0% | (20.2–53.2) | Total bilirubin | 0.5 mg/dL | (0.4–1.5) |
| Monocytes | 5.7% | (2.7–9.3) | AST | 19 U/L | (13–30) |
| Eosinophils | 0.6% | (0.2–4.1) | ALT | 16 U/L | (10–42) |
| Basophils | 0.3% | (0.2–1.3) | LDH | 200 U/L | (124–222) |
| RBC | 493×10/mm | (435–555) | ALP | 52 U/L | (38–113) |
| Hemoglobin | 14.3 g/dL | (13.7–16.8) | rGTP | 24 U/L | (13–64) |
| Hematocrit | 42.2% | (40.7–50.1) | Creatinine | 0.65 mg/dL | (0.65–1.07) |
| Platelets | 18.2×10/mm | (15.8–34.8) | BUN | 10 mg/dL | (8–20) |
| Natrium | 137 mEq/L | (138–145) | |||
| TSH | 93.87 µIU/mL | (0.5–5.0) | Potassium | 4.0 mEq/L | (3.6–4.8) |
| Free T3 | 2.0 pg/mL | (2.3–4.0) | Chlorine | 101 mEq/L | (101–108) |
| Free T4 | 0.6 ng/dL | (0.9–1.7) | Calcium | 9.2 mg/dL | (8.8–10.1) |
| Tg | 379.8 ng/mL | (0–33.7) | Glucose | 111 mg/dL | (73–109) |
| Tg-Ab | 401 IU/mL | (0–28) | HbA1c | 6.2% | (4.9–6.2) |
| TPO-Ab | 54 U/mL | (0–16) | T.chol | 186 mg/dL | (142–220) |
| TSH-R Ab | <0.8 U/L | (0–2) | |||
| Calcitonin | 0.5 pg/mL | (0–9.52) | |||
| CEA | 2.5 ng/mL | (0–5) | |||
| sIL-2R | 859 U/mL | (121–613) | |||
| Reference ranges are shown in parentheses. Ab – antibody; ALP – alkaline phosphatase; ALT – alanine transferase; AST – aspartate transaminase; BUN – blood urea nitrogen; CEA – carcinoembryonic antigen; HbA1c – hemoglobin A1c; LDH – lactate dehydrogenase; RBC – red blood cells; rGTP – γ-glutamyl transferase; sIL-2R – soluble interleukin-2 receptor; T3 – triiodothyronine; T4 – thyroxine; T.chol – total cholesterol; Tg – thyroglobulin; TPO – thyroid peroxidase; TSH – thyroid-stimulating hormone; TSH-R – thyroid-stimulating hormone receptor; WBC, white blood cells. | |||||