29 March 2025
: Case report 
Advancing Preoperative Diagnosis: Case Report and Imaging Analysis of Cervical Spine Tenosynovial Giant Cell Tumor
Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Wei Kong BCDEF 1, Yahong Shi BCDEF 1, Xin Zhao CD 2, Guoping Fang CD 3, Chenglei Liu ABCDEF 1*DOI: 10.12659/AJCR.946427
Am J Case Rep 2025; 26:e946427
Table 1. Imaging features of localized TGCT reported in the literature.
| Author | CT | MRI | ||||
|---|---|---|---|---|---|---|
| Location | Soft tissue mass | Bone destruction | T1WI | T2WI | Contrast | |
| Dingle et al, 2002 []2 | C4-5 | (+) | (+) | Nd | Hyper | ND |
| Doita et al, 2005 []3 | T7-8 | (+) | (+) | Hypo | Hypo, hyper | Obvious homo |
| Gupta et al, 2008 []4 | T8-9 | (+) | (+) | Iso | Hypo | ND |
| Blankenbaker et al, 2008 []5 | C1 | (+) | (+) | Hypo | Hypo | Mid homo |
| Teixeira et al, 2011 []7 | C1-2 | (+) | (-) | Nd | Hyper | Obvious homo |
| Okutan et al, 2012 []6 | C7 | (+) | (+) | Nd | Nd | Obvious homo |
| Ding et al, 2014 []8 | L 4-5 | (+) | (+) | Iso | Hyper | ND |
| Yamada et al, 2015 []9 | C1 | (+) | (-) | Iso | Hypo, hyper | Obvious homo |
| Furuhata et al, 2019 []10 | C1-2 | (+) | (-) | Iso | Hypo | Obvious hetero |
| Singh et al, 2020 []11 | C1 | (+) | (+) | Hypo | Hypo | Obvious homo |
| Zhu et al, 2021 []12 | C4-5 | (+) | (+) | Iso | Hypo | ND |
| Kim et al, 2021 []22 | C1-2 | (-) | (+) | Iso | Iso | Obvious hetero |
| Zeng et al, 2021 []1 | C5-7 | (+) | (+) | Hypo, hyper | Hypo, hyper | ND |
| C4-5 | (+) | (+) | Iso, hyper | Hyper, hypo | Obvious hetero | |
| C1-2 | (+) | (+) | Iso | Iso | ND | |
| C4-6 | (+) | (+) | Hypo, hyper | Hypo, hyper | ND | |
| C5 | (+) | (+) | Iso | Hypo | Obvious homo | |
| C1-2 | (+) | (+) | Iso | Hypo | ND | |
| C1 | (+) | (+) | Iso | Hypo | Moderate homo | |
| C4-5 | (+) | (+) | Hypo | Hypo | Obvious hetero | |
| C6 | (+) | (+) | Iso | Iso | ND | |
| C6-7 | (+) | (+) | Iso | Hypo | Moder homo | |
| T9 | (+) | (+) | Hypo | Hypo | Obvious hetero | |
| T1-2 | (+) | (+) | Iso | Hypo | Obvious homo | |
| T3 | (+) | (-) | Iso, hypo | Hyper | Obvious homo | |
| T8 | (-) | (+) | Iso | Iso | ND | |
| Zeolietet al, 2021 []13 | L5-S1 | ND | ND | Iso | Hyper, hypo | Obvious homo |
| Hu et al, 2022 []23 | C2 | ND | ND | Iso | Hyper | Obvious homo |
| Zhu et al, 2022 []24 | C1 | (+) | (-) | Iso | Hypo | ND |
| Shen et al, 2023 []25 | C1-2 | (+) | (+) | Hypo | Iso, hypo | ND |
| C1-2 | (+) | (+) | Hypo | Iso, hypo | ND | |
| C1-2 | (+) | (+) | Iso | Hypo | Obvious hetero | |
| Tsui et al, 2022 []16 | C1-2 | (+) | (+) | Hypo | Hypo | Mild homo |
| Song et al, 2023 []17 | T9-T10 | (+) | (+) | Iso | Hyper, hypo | Obvious hetero |
| CT – computed tomography; MRI – magnetic resonance imaging; T1WI – T1-weighted image; T2WI – T2-weighted image; iso – isointense; hypo – hypointense; hyper – hyperintense; ND – no data. | ||||||