Acremonium strictum Sphenoid Sinusitis in an Immunocompetent Patient

08 April 2025 : Case report China

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease

Yuting Wang^1BCDEF, Qingzhong Liu^1ACF, Huiming Sheng

^2BD, Shuohui Yang^3CEF*

DOI: 10.12659/AJCR.946501

Am J Case Rep 2025; 26:e946501

Introduction Case Report Discussion Conclusions References:

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Table 2. Cases of Acremonium strictum infection reported in the literature.

References	Report year	Age/sex	Country	Infection site	Disease situation	Treatment	Outcome
Ibrahim H []¹⁴	2023	62 years old/M	Egypt	Fungal brain	Diabetic and had a history of Hodgkin’s lymphoma	Amphotericin B, fluconazole	Died
Liu J []¹¹	2021	86 years old/F	Toronto	Fungal keratitis	Therapeutic penetrating keratoplasty (TPK)	Amphotericin B, voriconazole	Cured
Tendo C []¹²	2021	55 years old/F	UK	Keratitis	History of episcleritis	Voriconazole	Cured
Jalan D []¹⁵	2021	19 years old/F	India	Fungal osteomyelitis of calcaneus	Immunocompetent	Ketoconazole	Cured
Hilmioglu S []¹⁷	2015	45 years old/F	Turkey	Both legs	Obesity and gonarthrosis	Amphotericin B, itraconazole	Cured
Virgilio E []¹⁸	2015	23 years old/M	Italy	Thoracentesis	Metastatic testicular teratocarcinoma	Amphotericin B	Died
Sharma A []¹⁰	2013	33 years old/F	India	Cutaneous infection	None	Terbinafine, terbinafine	Cured
Hitoto H []¹⁹	2010	10 years old/M	France	Fungaemia	Immunocompromised Leukemic (AML)	Amphotericin B, voriconazole	Cured
Guarro J []¹³	2009	73 years old/M	Spanish	Endocarditis	Prosthetic valve dysfunction	Not known	Died
KoÇ AN []²⁰	2008	77 years old/F	Turkey	Pleural fluid	Colon adenocarcinoma	Died before antifungal, treatment	Died
Sener AG []¹⁶	2008	47 years old/F	Turkey	Peritonitis	Diabetes mellitus; continuous ambulatory peritoneal dialysis (CAPD)	Fluconazole	Cured
F – female; M – male.

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