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06 January 2025 : Case report  Australia

Severe Hypomagnesemia and Hypocalcemia Linked to Semaglutide in Type 2 Diabetes: A Case Report

Unusual clinical course, Unusual or unexpected effect of treatment, Adverse events of drug therapy

Timothy Mark Earls Davis12ABCDEFG*

DOI: 10.12659/AJCR.946539

Am J Case Rep 2025; 26:e946539

Table 1. Laboratory test results on admission to the hospital.

VariableAdmission valueReference interval
Serum sodium138 mmol/L135–145 mmol/L
Serum potassium4.2 mmol/L3.5–5.2 mmol/L
Serum bicarbonate18 mmol/L22–32 mmol/L
Serum urea6.4 mmol/L4.0–9.0 mmol/L
Serum creatinine87 μmol/L45–90 μmol/L
Estimated glomerular filtration rate56 mL/min/1.73 m>60 mL/min/1.73 m
Serum albumin33 g/L35–50 g/L
Serum magnesium<0.3 mmol/L0.7–1.1 mmol/L
Serum total corrected calcium1.90 mmol/L2.10–2.60 mmol/L
Serum ionized calcium0.85 mmol/L1.15–1.30 mmol/L
Serum glucose11.5 mmol/L3.5–6.9 mmol/L
Blood lactate2.2 mmol/L0.4–2.0 mmol/L
HbA8.6% (70 mmol/mol)<6.0% (<42 mmol/mol)

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923