A Rare Case of Severe Pernicious Anemia with Neuropsychiatric Implications

25 May 2025 : Case report USA

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Stanley Kim

^{ABCDEFG 1*}, Jade Punzalan^{BCDEF 2}, BreeAnna Carlson

^{BCDEF 3}

DOI: 10.12659/AJCR.946911

Am J Case Rep 2025; 26:e946911

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Table 1 Laboratory test results from Day 1 to Day 15 of admission.

	WBC	Hb/MCV	PLT	RET	MMA	HCY	BUN	CR	B12	SF	PRBC
D1	4.3	2.5/133	140	2.7	34,920	198.4	41	1.52	72	11.6	1 unit
D2	3.0	2.5/124	111				36	1.35			1 unit
D3	5.1	2.6/123	102				26	1.23			1 unit
D4											1 unit
D5	26.5	3.1/133	78				16	0.93			1 unit
D6	13.8	4.0/138	94				16	0.95			1 unit
D7	8.8	7.3/107	132	20.7			17	0.84
D8	6.3	7.9/109	163		1,299		19	0.84	5318	6.1
D9	7.0	8.1/107	236				22	0.78
D15	10.4	9.2/102	824				27	0.92	899
Hb – hemoglobin (g/dL); MCV – mean corpuscular volume (fL); PLT – platelet (10/L); RET – reticulocyte (%); MMA – methylmalonic acid (mol/L); HCY – homocysteine (mmol/L); BUN – blood urea nitrogen (mg/dL); CR – creatinine (mg/dL); B12 – vitamin B12 (pg/dL); SF – serum folate (ng/mL); PRBC – packed red blood cells.

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