07 May 2025
: Case report 
A Rare Case of Hypoxia and Cyanosis Secondary to Multifactorial Medication-Induced Sulfhemoglobinemia
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons
Megan M. Mansour BE 1, Robert M. Seby BE 1, Aya Elalfy BDEF 1, Mario El Hayek BCDE 2, Tuhama S. Rihani CDE 3,4, Edson J. Mwakyanjala CDE 3,4, Libardo Rueda Prada
ABCDEFG 3,4*
DOI: 10.12659/AJCR.947587
Am J Case Rep 2025; 26:e947587
Table 2 List of common substances associated with sulfhemoglobinemia. Medications associated with our presented case highlighted in bold text.
| List of common substances associated with sulfhemoglobinemia [1,8,10] | |
|---|---|
| AcetanilidAminophenolp-AminopropiophenoneAmmonium nitriteAmyl nitriteAnilineAnilinoethanol | MetoclopramideMethylacetylanilide |
| NaphthylamineNitritesp-NitroanilineNitrobenzeneNitroglycerin | |
| Bismuth subnitrite | |
| DapsoneDimethylamineDinitrobenzene | PhenacetinPhenylenediaminePhenylhydroxylamine |
| Ethyl nitrite | SulfanilamideSulfapyridineSulfathiazoleSumatriptan |
| Flutamide | |
| ToluenediamineTolylhydroxylamineTrinitrotoluene | |
| HydroxylacetylanilideHydroxylamine | |