13 August 2025
: Case report 
Cryotherapy via Flexible Bronchoscopy for Pediatric Plastic Bronchitis: A Case Report
Unusual or unexpected effect of treatment
Fang Jin ABCDEF 1,2, Xiaofen Tao
EF 1,2, Hujun Wu EF 1,2, Lei Wu ABCD 1,2, Yingshuo Wang EF 1*
DOI: 10.12659/AJCR.947838
Am J Case Rep 2025; 26:e947838
Table 1 Summary of the application of bronchoscopic cryotherapy in the removal of foreign bodies or endogenous foreign substances over the past 5 years.
| Year of publication | 2023 | 2022 | 2022 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|---|
| Anshula Tayal et al | Roser Ayats-Vidal et al | Dvir Gatt et al | Michelle M. Ojard et al | Fernando Figueroa Rodriguez et al | Dengyuan Li et al | |
| 2 | 1 | 1 | 1 | 1 | 1 | |
| 16 m; 2 y | 9 y | 4.5 y | 47 y | 72 y | 74 y | |
| Boy; Girl | Boy | Boy | Woman | Man | Man | |
| Case 1: cough and irritability for 1 week and fever for 2 days;Case 2: acute coughing and choking after consumption of almonds | 3 months of intermittent harsh cough and pulmonary congestion | Prolonged fever, weight loss, and weakness | Bleeding in the posterior-oropharynx in association with severe pancytopenia and mucositis | Hypoxemic respiratory failure related to COVID-19 pneumonia | Hemoptysis, cough, and pharyngeal discomfort for 45 days | |
| Case 1: fever, cough, and irritability;Case 2: acute coughing and choking | Cough and respiratory distress | Fever, weight loss, weakness, and respiratory distress | Bleeding, respiratory distress | Hypoxemic respiratory failure | Hemoptysis, cough, and pharyngeal discomfort | |
| Case 1: reduced breath sounds and monophonic wheeze on the left side;Case 2: breath sounds were reduced and wheeze was audible in left infrascapular region | Bilateral rhonchi and isolated intermittent wheezing | Decreased air entry to the left lung | – | – | No abnormal findings | |
| Case 1: Fogarty balloon and cryoprobe;Case 2: Fogarty balloon and cryoprobe | Forceps, airway balloon, basket, cryoprobe | Cryoprobe | Cryoprobe | Cryoprobe | Cryoprobe | |
| Case 1: half a cotyledon of peanut;Case 2: a small piece of almond | A cuttlefish with surrounding inflamed granulation tissue | A massive blood clot | A cast of the left bronchial tree | A massive blood clot | A leech | |
| Case 1: 1 mCase 2: 1 y | 2 m | Not clear | – | Not clear | 1 w | |
| Doing well | Returned to normal | Recovered completely | – | Improved | Returned to normal |