Management of Cardiac Tamponade During Systemic Lupus Erythematosus Flare with Significant Pericardial Effusion: A Case Report

23 August 2025 : Case report Australia

Challenging differential diagnosis, Management of emergency care, Rare disease, Clinical situation which can not be reproduced for ethical reasons

Adam D. Walsh

^{ABCDEFG 1*}, Mitchell T. Carroll^{E 1}

DOI: 10.12659/AJCR.947859

Am J Case Rep 2025; 26:e947859

Authors information Article notes Copyright and License information

Introduction Case Report Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 1 Large pericardial effusions with tamponade in the literature and subsequent management.

Reference	Clinical details	Size of effusion	Management
Larson et al []¹⁵	18M new diagnosis SLE with chest pain	1500 mL	Pericardiocentesis, corticosteroids, hydroxychloroquine
Stone et al []¹⁰	32F relapsed SLE with hypotension and pulsus paradoxus	1300 mL	Pericardial fenestration, corticosteroids, mycophenolate
Kise et al []¹⁴	15F relapsed SLE with chest pain and fever	525 mL	Pericardiocentesis, corticosteroids, belimumab, hydroxychloroquine.
Felani and Awalia []¹⁶	33F relapsed SLE in the setting of pregnancy	1613 mL	Pericardial drain over 4 days, corticosteroids, mycophenolate
Kumar et al []¹⁷	17F new diagnosis SLE with retrosternal chest pain	1000 mL	Pericardial window, corticosteroids, colchicine

Back to the Article