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05 August 2025 : Case report  Japan

Recurrent Severe Hyponatremia Following Polyethylene Glycol Electrolyte Lavage Solution with Ascorbic Acid in a Patient with Undiagnosed Syndrome of Inappropriate Antidiuretic Hormone Secretion

Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)

Koichi Soga ORCID logo ABCDEFG 1*, Yuto Suzuki BE 1, Fuki Hayakawa BE 1, Takeshi Fujiwara BE 1, Takahiro Ota BE 1, Ikuhiro Kobori ORCID logo BE 1, Masaya Tamano BE 1

DOI: 10.12659/AJCR.948355

Am J Case Rep 2025; 26:e948355

Table 3 Differences in PEG-ELS/Asc and PEG-ELS.

PEG-ELS/AscPEG-ELS
2 L2 L
244.212 g per bag137.155 g per bag
Sodium chloride5.382 g2.93 g
Potassium chloride2.03 g1.485 g
Sodium sulfate15.0 g11.37 g
Macrogol 4000 (polyethylene glycol)200.0 g118 g
Ascorbic acid9.4 g
L-sodium ascorbate11.8 g
Na182 mEq/L125 mEq/L
K14 mEq/L10 mEq/L
pH4.38
Osmotic pressure ratio (plasma)1.91
K – potassium; Na – sodium; PEG-ELS – polyethylene glycol electrolyte lavage solution; PEG-ELS/Asc – polyethylene glycol electrolyte lavage solution with ascorbic acid.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923