27 September 2025
: Case report
Restoration of Cardiac Function in Left Bundle Branch Block-Induced Cardiomyopathy via Conduction System Pacing: A Case Report
Unknown etiology, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Jing Wang BDEF 1, Bing Han AB 2, Xiaojuan Wang BDF 2, Zixian Chen BC 3, Wenqiang Li ABDE 4,5*DOI: 10.12659/AJCR.948576
Am J Case Rep 2025; 26:e948576
Table 2 Changes in echocardiographic and cardiac synchrony parameters before and after CSP.
| Baseline | Pre-CSP | CSP | 4 Months after CSP | 6 Months after CSP | 30 Months after CSP | |
|---|---|---|---|---|---|---|
| QRS (ms) | 78 | 132 | 95 | – | 82 | 82 |
| LVEF (%) | 55 | 34 | 38 | 50 | 54 | 56 |
| SV (ml) | 68 | 68 | 70 | 55 | 57 | 65 |
| LVEDV (ml) | 123 | 223 | 184 | 111 | 105 | 116 |
| Global strain (%) | – | −8.1 | −10.1 | – | −16.5 | – |
| Ts-SD (%) | – | 9.88 | 6.7 | – | 2.27 | – |
| CSP – conduction system pacing; LVEF – left ventricular ejection fraction, SV – systolic volume, LVEDV – left ventricular end-diastolic volume, Ts-SD – segmental standard deviation of time to peak systolic contraction. | ||||||






