12 December 2025
: Case report 
Heterozygous Variants of the SLC39A4 Gene and Possible Increased Risk for Developing Acrodermatitis Enteropathica with Kaposi’s Varicelliform Eruption
Unusual clinical course
Yuan He ABCDEF 1, Liu Bai ABCDEF 1, Junyou Li ABCDEFG 1*DOI: 10.12659/AJCR.948668
Am J Case Rep 2025; 26:e948668
Table 1 Patient and family clinical profile.
| Parameter | Patient | Mother | Father |
|---|---|---|---|
| Age | 8 years 11 months | 28 years | 33 years |
| Origin | Eastern China | Eastern China | Eastern China |
| Consanguinity | Not applicable | None (unrelated) | None (unrelated) |
| Serum zinc (μg/dL) | 76.13 (Ref: 70–120) | Not tested | Not tested |
| ALP (U/L) | 32 (Ref: 143–406) | Not tested | Not tested |
| HSV1/2-IgG | Positive | Negative | Negative |
| Carrier status | Compound heterozygous | c.522_523dup het | c.925T>C hetc.1782C>T hetc.1843C>T het |
| ALP – alkaline phosphatase; HSV – herpes simplex virus. | |||