12 September 2025
: Case report 
Isolated Sensorineural Hearing Loss as the Sole Manifestation of Granulomatosis with Polyangiitis
Unusual clinical course, Challenging differential diagnosis, Management of emergency care
Alejandro Arango
ABCDEF 1*, Sehreen Mumtaz ABCDEF 2, Andy Abril ABCDEF 2
DOI: 10.12659/AJCR.948700
Am J Case Rep 2025; 26:e948700
Table 2 Previously published cases of otological involvement in GPA.
| Author | Sex | Age | Type of HL | Pattern of HL | Other manifestations | Treatment |
|---|---|---|---|---|---|---|
| Kim et al (2016) []16 | Male | 47 | SNHL | Bilateral | GPA, facial paralysis, vertigo | Steroids, CYC, RTX |
| Ratmeyer et al (2021) []17 | Female | 72 | SNHL | Bilateral | Pulmonary, glomerulonephritis | MTP, CYC |
| Wawrzecka et al (2015) []18 | Female | 56 | SNHL | Bilateral | Otalgia, facial palsy, renal & lung GPA | Steroids, CYC |
| HL – hearing loss; SNHL – sensorineural hearing loss; GPA – granulomatosis with polyangiitis; MTP – methylprednisolone; CYC – cyclophosphamide; RTX – rituximab. | ||||||