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07 August 2025 : Case report  USA

Chemotherapy without Blood Products for Treatment of Acute Myelogenous Leukemia in an Anemic Jehovah’s Witness Patient

Unusual clinical course, Unusual setting of medical care, Clinical situation which can not be reproduced for ethical reasons

Rida Altaf ABCDE 1, Mousa Thalji EF 2, Sarah Crowder BDE 1, Kiera Brigh Turner BEF 1, Hatem Hassanein CE 2, Stephen Carlan CEF 3*

DOI: 10.12659/AJCR.949145

Am J Case Rep 2025; 26:e949145

Table 1 Laboratory values on initial admission, before chemotherapy, color-coded by exceptions to normal ranges.

Laboratory test results on first admissionNormal RangeAbbreviationValue
Hemoglobin (g/dL)Women: 12.3 to 15.3 g/dLHb7.2Low value
Hematocrit (%)Women: 36% to 48%HCT22
Mean corpuscular volume (fL)80–100 fLMCV118.9High value
Mean corpuscular hemoglobin (pg/cell)27 to 33 pg/cell (red blood cells)MCH38.9
White blood cell count (cells/μL)4500–11 000 cells/μLWBC3000Low value
Platelets (×10/L)100 000–400 000/LPLT199 000Normal value
Serum vitamin B12 (pg/mL)200–800 pg/mLB12594
Serum folate (ng/mL)>3.5 ng/mLFOL8.3
Serum iron (mcg/dL)Women: 50 to 170 mcg/dLFe101
Serum transferrin (mg/dL)Women: 250–370 mg/dLTRF305
Total iron-binding capacity (mcg/dL)Women: 149–492 mcg/dLTIBC381
Percent iron saturation (%)Women: 15–45%%SAT27
Serum ferritin (ng/mL)Women: 13–150 ng/mLSF318.3High
Absolute reticulocytes (cells/μL)19 000–124 000/μLARC60 700Normal
Reticulocyte percentage (%)0.5–2.2%Retic%3.23High
Reticulocyte index (%)0.5–2.5%RI0.85Normal value
Reticulocyte red blood cell count3.75–5.00×10/μLRetic1.88
Direct antiglobulin testNegativeDATNegative
Lactic dehydrogenase (U/L)105–233 U/LLDH225
Hemoglobin F electrophoresis (HbF%)<1%HbF2.8High
Blood pressure120/80BP113/71
Oxygen saturation95–100%O2Sat100
High lab value
Normal lab value
Low lab value

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923